Vitamin D2 As I{umoral Immunosuppressent in Rabbit | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 1, Issue 2, August 2004, Pages 177-181 | ||
| Authors | ||
| ; ; Ibrahim M.S. Shnawa | ||
| Abstract | ||
| Serial concentrations of vitamin D, that ranges liom 1.7-34 ru were made in 2% egg albumin aqious solution and used for rabbit pdming ihrough multisite and o|al protocols. Meantime, same viiamin D, concentration incorporated in the diluting buffur ofthe h,?erinrmune and immunesera ofanti EA specificity and titred against egg albumin coated erythrccltes. The imnunornodulation effe€t was scored as either titre eDhancement or titer rcduction .vit. D, was found as being humorai immunosuppressant and of dose dependent type . The dose r€sponse relationship was of simple linear t)?e . Such $ppression effect was evident bolh invivo dxdng the immune response time cuve and jnvitro on rcady made anti EA anxibody titers .The hurnoral jmmunotoxiciry parameters as NOL tircshold and activity range were determined vit. D, can be ofhelp in maintenance and t|eatment of autoimmxne disease and elafi incomDatibilitv conditions. | ||
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