A. Al-Mudhaffar, S., J. M. Al-Rawi, B. (2004). Radio Receptor Asspy Studies of 125 l-Testosterone Binding to its Receptors in Benign and Malignant Human Uterine Tumors. Alustath, 1(2), 137-148.
Sami A. Al-Mudhaffar; Bilal J. M. Al-Rawi. "Radio Receptor Asspy Studies of 125 l-Testosterone Binding to its Receptors in Benign and Malignant Human Uterine Tumors". Alustath, 1, 2, 2004, 137-148.
A. Al-Mudhaffar, S., J. M. Al-Rawi, B. (2004). 'Radio Receptor Asspy Studies of 125 l-Testosterone Binding to its Receptors in Benign and Malignant Human Uterine Tumors', Alustath, 1(2), pp. 137-148.
A. Al-Mudhaffar, S., J. M. Al-Rawi, B. Radio Receptor Asspy Studies of 125 l-Testosterone Binding to its Receptors in Benign and Malignant Human Uterine Tumors. Alustath, 2004; 1(2): 137-148.

Radio Receptor Asspy Studies of 125 l-Testosterone Binding to its Receptors in Benign and Malignant Human Uterine Tumors

Medical Journal of Babylon
Article 1, Volume 1, Issue 2, August 2004, Pages 137-148
Authors
Sami A. Al-Mudhaffar; Bilal J. M. Al-Rawi
Abstract
A Radio receptor assay procedure was developed for the determination oftestosterone receptors in
two groups of human uterine tumor
patients (b€nign and malignano. The optimum conditions of the
bindiry ofrz5l-testosterone to the receptors were as follows: receptor concentration: (250
ug
proteh),
tracer tesiosterone concentration (0.9 ng per 100!
),
time (8 fu), pH (8.0) and tempemtues (4 and
25"C) for benign and malignani tumors respectively.
Incubation of u{abeled testosterone and estradiol with uterine tumor tissue homosenate inhibited
the ability of
]'?sl-testosterone
to binal the uterire tissue lomogenate, whiie Eogestede
in-hibjted the binding slightly.
The use of0.1 M ofsodiurn halides and 0.025 M of divalent salts wore shown lo cause differ€nt €ffects
on the binding in the two
groups
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