The Kinetic anal The Therrnodynamic Studies on the Binding of 125 I -Testosterone to Its Receptors in Uterine Tumors Homogenate | ||
Medical Journal of Babylon | ||
Article 1, Volume 1, Issue 1, April 2004, Pages 74-90 | ||
Authors | ||
Sami A. Al-Mudhaffar; Bilal J.M. AI-Rawi | ||
Abstract | ||
Kinetic and thermodynamic studies were carried out on the uterine tumor homogenate binding to l25l-testost".oua. i'i,',"-"ou.." ofthe association oflt5l-testosterone with its receptor in human ute ne tumors at four different temperatures revealed the time and temperature dependency' Association kinetics ildicated pseudo first order kinetics for the binding. Time-courses, scatchard, Van't Hoffs and Arrhenius plots led to the theoretical determination of thermodynamic parameters ofbo*r the standard state (i.e., AH', AG', ASo) and transition state (i e , AH+, AG*, AS*) | ||
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