Activity of Alanine aminopeptidase and its isoenzyms partially purified from the urine of chronic renal failure patients. | ||
Kirkuk Journal of Science | ||
Article 1, Volume 3, Issue 2, December 2008, Pages 11-22 PDF (0 K) | ||
Document Type: Research Paper | ||
DOI: 10.32894/kujss.2008.42148 | ||
Authors | ||
Ferah G. Al-Salihi1; Tagreed U. AL-Akabie2 | ||
1College of Education for women - University of Tikrit | ||
2College of Education - University of Tikrit | ||
Abstract | ||
The study was performed on 50 urine specimens of patients with chronic renal failure ,in addition to the 92 healthy specimens as a control group. The results of the study revealed that Alanine aminopeptidase (AAP) activity of chronic renal failure patients urine shows a highly significant increase (p<0.0001) compared to healthy subjects. Alanine aminopeptidase was purified from urine patients with chronic renal failure and healthy subjects by gel filtration using sephadex G-50, and two isoenzyms of (AAP) I, II were separated from patients urine using anion exchanger (DEAE-sephdexA-50). | ||
Keywords | ||
activity; Alanine; aminopeptidase; its isoenzyms; partially; purified from; urine; chronic renal failure patients; AAP | ||
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