Effect of Petrolium ether extract of Carrot Plant Seeds Dacus carota L. as antifertility on Female White rats | ||
| Magazine of Al-Kufa University for Biology | ||
| Article 1, Volume 4, Issue 1, June 2012, Pages 210-222 | ||
| Abstract | ||
| This study was conducted to recognize the effect of of petroleum ether extract of Dacus carota L. as antifertility to female white ( Rattus ratus), The study was performed in the animal Laboratory of Biology department in the Science Collage / University of Kufa throughout the period from (25/9/2010) to (20/3/2011) , in this study female white(Rats) were usedincluding (76) rats , the age of these females wereabout (8-12) weaks , here Suplemented by different concentrations (50 , 100 , 200) mg / kg of extract for three period of (10 , 15 , 20) days .The results of this study were revealed the followings : • Asignificant decrease (P<0.05) in the weights of Reproductive organs (ovaries) of female white rats at all concentration (50 , 100 , 200) mg / kg and periods (10 , 15 , 20) days was highy effective in reducing the ovarian weight in The concentration (200) mg / kg and the period of (20) day comparing with the control group and other concentrations and periods . .• Asignificant increase (P<0.05) in the weight of Uterus at all concentrations(50 , 100 , 200) mg / kg and all period of (10 , 15 , 20) day The concentration (200) mg / kg and the period of (20) days was highy effective than other concentrations and the periods increment of Uterine Weight • Asignificant decrease (P<0.05) in the hormone levels : Follicle stimulating hormone (FSH) and Luteinizing hormone (LH) and Asignificant increase (P<0.05) in the Estradiol hormone level and the concentration (200) mg / kg and period of (20) day was highy significant comparing with the control group and other concentrations. • The histological study was showed asignificant decrease(P<0.05) in the numbers of Primary , Secondary ovarian follicles and Graffian follicles and this study was showed Asignificant increase (P<0.05) in thickness of Endometrium of Uterus of female white rats and this study showed that the large significant (P<0.05) was in the concentration (200) mg / kg and period of (20) day comparing with the control group .• The results of female fertility have not been showen presence of sperm in vaginal smear unless beyond aperiod of time and pregnancy period would be late through dialy watchingfor (60) day. Aclear decrease in percent of pregnancy and in numbers of embryos of female White rats that treated by the concentration(50 , 100 , 200) mg / kg comparing with the control group . The study was Concluded that Petrolium ether of Carrot Seed act as antifertility by their effect on embryos numbers , pregnancy percent and hormonal leves (FSH , LH and Estradiol) . | ||
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