Effect of the alcoholic extract of Achillea santolina on Reproductive organs of male in albino mice Mus musculus | ||
| Magazine of Al-Kufa University for Biology | ||
| Article 1, Volume 4, Issue 1, June 2012, Pages 79-87 | ||
| Abstract | ||
| This experiment was designed to test the effect of the alcoholic extract of Achillea santolina on fertility of male mice ,the treatment cause a number of pathological changes in the tissues of testes and epididymis . 1n this study was used (24) of the albino mice male of Balb/c breed , these mice were divided randomly in to a control group and three experiment groups were treated of concentration (200,250,300) mg/kg intrapertonealy for 25 daily.These study results were revealed the chemical analysis of the extract that contain secondary compound , alkaloid ,terpenoid , saponins , phenols and glycosides .there was a significant decrease (P<0.05) in avearage of treated animals body weight at all concentration as compared with the control group and there was significant differences between treated groups .the treatment with alcoholic extract of Achillea santolina plant has been resulted in many pathological changes in the germinal epithelium tissue that is lined testes as well as in epithelial cells which are lined epididymal tubules It could be concluded that the alcoholic extract of Achillea santolina plant may have a pathological effect on testes ,epididymis in albino male mice which may influences the fertility. | ||
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