Extraction of Penicillin V from Simulated Fermentation Broth by Liquid-Liquid Membrane Technique | ||
| Al-Khwarizmi Engineering Journal | ||
| Article 1, Volume 8, Issue 2, June 2012, Pages 77-83 | ||
| Author | ||
| Khalid W. Hameed | ||
| Abstract | ||
| Liquid-liquid membrane extraction technique, pertraction, using three types of solvents (methyl isobutyl ketone, n-butyl acetate, and n-amyl acetate) was used for recovery of penicillin V from simulated fermentation broth under various operating conditions of pH value (4-6) for feed and (6-8) for receiver phase, time (0-40 min), and agitation speed (300-500 rpm) in a batch laboratory unit system. The optimum conditions for extraction were at pH of 4 for feed, and 8 for receiver phase, rotation speed of 500 rpm, time of 40 min, and solvent of MIBK as membrane, where more than 98% of penicillin was extracted. | ||
| Keywords | ||
| liquid; liquid membrane; Penicillin V; pertraction; extraction | ||
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