Anti-fungal Activity of Punica Granatum I.peels Powder and Extracts from Pathogenic Samples | ||
| Iraqi Journal of Pharmaceutical Sciences | ||
| Article 1, Volume 16, Issue 2, December 2007, Pages 12-20 | ||
| Authors | ||
| Hassan J.Mohamm; Hamoudi A.Hameed; Siham S.Shaokat | ||
| Abstract | ||
| Thirty five samples were collected from patients (1-30) years old, suffered from, infected skin , rushes, boils , oral thrush, anal & vaginal itches. Candida albicans 57.3% (20 isolates) and Candida tropicalis 22.5% (8 isolates) Aspergillus fumegatus 11.5% (4 isolates) Aspergillus nigar 8.7%(3 isolates) , were isolated & identified from these samples. Alcoholic & water hot extracts of the punica granatum (Pomegranate) peels as well as the dried powder were prepared. The anti-fungal activity of the extracts was evaluated by means of the agar-well diffusion assay. The extract exhibited potent activity against yeast. The Minimum inhibitory concentrations were 128-1024 μg/ml against Candida albicans and Candida tropicalis .Their was little difference between the activities of alcoholic extract & aqueous extract. These results suggest the Pomegranate Peels extract which contains gallotanic acid as a promising anti-fungal agent. | ||
| Keywords | ||
| Antifungal agents; Plant Extracts; Candida isolation | ||
|
Statistics Article View: 23 PDF Download: 7 |
||