Comparative study between Immunohistochemistry and Molecular method in detection of BRAF V600E mutation in papillary thyroid carcinoma | ||
| Basrah Journal of Surgery | ||
| Article 9, Volume 29, Issue 2 - Serial Number 58, December 2023, Pages 76-87 PDF (888.54 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.33762/bsurg.2023.144308.1062 | ||
| Authors | ||
| Sarah Ali Darweesh* 1; Jasim M. Al-Diab2; Sawsan S. Al-Harron3; Hussam Aziz Hasson4 | ||
| 1Hitopathology Resident, Basrah Teaching Hospital, Basrah, Iraq | ||
| 2Professor of pathology. College of Medicine. University of Basrah. | ||
| 3Department of Pathology, faculty of Medicine, University of Basrah, Iraq.) | ||
| 4Lecturer،Southern Technical University, College of Medical Lab Technologies | ||
| Abstract | ||
| Papillary thyroid carcinoma is the most common endocrine and thyroid malignancy. The (BRAF V600E) mutation is the most common mutation in papillary thyroid cancer (PTC). The mutation is detected in about (60%) of the cases. Patients with BRAF mutation have been linked to aggressive clinical behavior, high recurrence rate, metastasis, and failure of treatment. | ||
| Keywords | ||
| Papillary thyroid carcinoma,,; ,،IHC,,; ,،PCR,,; ,،BRAF | ||
| References | ||
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