Unexpected Presentation for predicted Complication Orbital Lymphoma in a patient with Primary Sjögren Syndrome | ||
| The Medical Journal of Basrah University | ||
| Volume 41, Issue 2, December 2023, Pages 139-145 PDF (479.58 K) | ||
| Document Type: Case Report | ||
| DOI: 10.33762/mjbu.2023.145199.1179 | ||
| Authors | ||
| Mustafa E. Omran Omran* 1; Asaad khalaf* 2; Raghda Saleem* 3 | ||
| 1Lecturer, Department of Medicine, Al-Zahraa College of Medicine, University of Basrah, Basrah, Iraq | ||
| 2Haematology Subspecialty senior, Head of Haematology Department, Al-Sayyab Teaching Hospital, Basrah, Iraq | ||
| 3University of Basrah | ||
| Abstract | ||
| Lymphoid malignancies are the most common primary orbital tumours but they constitute only 2% of extranodal lymphomas. A fifty-year-old lady known case of SS presented with progressive blurred vision and left deep orbital pain for about 5 months duration, with time, she started to develop left eye protrusion with ophthalmoplegia. The histopathological diagnosis was a low-grade follicular (nodular) B cell subtype of non-Hodgkin lymphoma (Grade 2). Immunohistochemically, it displayed CD45 and CD20 positive, stained whole neoplastic variables sizes follicles, CD3 stained rime of non-neoplastic T cells around the follicles. Positron Emission Scan (PET scan) exhibited mild hyper-metabolic multiple right cervical and supraclavicular lymph nodes. Moderately hypermetabolic enlarged abdominal (Left Para-aortic, bilateral common iliac, right external and inguinal lymph nodes). The patient after the 4th cycle of chemotherapy has no palpable cervical lymphadenopathy and restores normal vision in the left eye. | ||
| Keywords | ||
| Sjogren syndrome; orbital lymphoma; basrah | ||
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