Sukar Mezedawee, A., Khudair, S. (2023). Exploring the Influence of Neutrophil-Lymphocyte Ratio, D-Dimer, C - Reactive protein, and Ferritin on Outcome Prediction of Severely-Ill Patients with COVID-19 in Al-Sader Medical City in Al-Najaf City, Iraq. Alustath, 22(3), 280-285. doi: 10.52573/ipmj.2023.181134
Ameer Ali Sukar Mezedawee; Safaa Ali Khudair. "Exploring the Influence of Neutrophil-Lymphocyte Ratio, D-Dimer, C - Reactive protein, and Ferritin on Outcome Prediction of Severely-Ill Patients with COVID-19 in Al-Sader Medical City in Al-Najaf City, Iraq". Alustath, 22, 3, 2023, 280-285. doi: 10.52573/ipmj.2023.181134
Sukar Mezedawee, A., Khudair, S. (2023). 'Exploring the Influence of Neutrophil-Lymphocyte Ratio, D-Dimer, C - Reactive protein, and Ferritin on Outcome Prediction of Severely-Ill Patients with COVID-19 in Al-Sader Medical City in Al-Najaf City, Iraq', Alustath, 22(3), pp. 280-285. doi: 10.52573/ipmj.2023.181134
Sukar Mezedawee, A., Khudair, S. Exploring the Influence of Neutrophil-Lymphocyte Ratio, D-Dimer, C - Reactive protein, and Ferritin on Outcome Prediction of Severely-Ill Patients with COVID-19 in Al-Sader Medical City in Al-Najaf City, Iraq. Alustath, 2023; 22(3): 280-285. doi: 10.52573/ipmj.2023.181134

Exploring the Influence of Neutrophil-Lymphocyte Ratio, D-Dimer, C - Reactive protein, and Ferritin on Outcome Prediction of Severely-Ill Patients with COVID-19 in Al-Sader Medical City in Al-Najaf City, Iraq

Iraqi Postgraduate Medical Journal
Article 7, Volume 22, Issue 3, July 2023, Pages 280-285    PDF (215.86 K)
DOI: 10.52573/ipmj.2023.181134
Authors
Ameer Ali Sukar Mezedawee* 1; Safaa Ali Khudair* 2
1Ministry of Health \ Al-Sader Medical City\ Najaf Governorate \ Iraq.
2Internal Medicine, College of Medicine, University of Kufa, Najaf, Iraq.
Abstract
BACKGROUND:
Coronaviruses are microorganisms of animal and mankind. The WHO categorized the disease    as COVID-19 in February, 2020. 
Various laboratory markers can support the identification and follow up of COVID-19 case. Current evidence proposes a prognostic impact of neutrophil-lymphocyte ratio (NLR) in diverse inflammatory syndromes. Hence, it is rationalized to investigate its role as a prognostic biomarker in severe COVID‐19 pneumonia.
OBJECTIVE:
The objective is to analyze the effect of NLR, D-dimer, CRP, and ferritin role in the prediction of consequence of inpatients with severe COVID-19.
METHOD OF THE STUDY:

A retrospective cross-sectional study was conducted on 96 patients aged (18-80) years whom PCR SARS-CoV-2 positive, and admitted to (Al-Sader Medical City) in Al-Najaf City, Iraq between (July to October 2020).
The absolute number of neutrophil count divided by the absolute number of lymphocyte count is measured on admission to determine the value of (NLR). Parameters like (D-dimer, C-reactive protein, and ferritin) also have been investigated in relation to outcome.

RESULT:
High (NLR) was significantly (p-value = 0.001) linked with lower oxygen concentration and worse prognosis.
CONCLUSION:
Raised (NLR) was a convenient indicator connected with unfortunate outcome in those admitted with COVID-19. High inflammatory markers, like ferritin, CRP, and D-dimer were also associated with doomed prognosis.
 
Keywords
coronaviruses; neutrophil to lymphocyte ratio; prognosis
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