Mohammed, W., Warwar, A., Awad, F. (2023). A promising strategies for reducing the danger of SARS-CoV2 transmission during dentistry and medical procedures. Alustath, 17(1), 42-49. doi: 10.37652/juaps.2023.178811
Waleed Khalid Mohammed; Abdul Nasser H. Warwar; Fatimah Abdulazeez Awad. "A promising strategies for reducing the danger of SARS-CoV2 transmission during dentistry and medical procedures". Alustath, 17, 1, 2023, 42-49. doi: 10.37652/juaps.2023.178811
Mohammed, W., Warwar, A., Awad, F. (2023). 'A promising strategies for reducing the danger of SARS-CoV2 transmission during dentistry and medical procedures', Alustath, 17(1), pp. 42-49. doi: 10.37652/juaps.2023.178811
Mohammed, W., Warwar, A., Awad, F. A promising strategies for reducing the danger of SARS-CoV2 transmission during dentistry and medical procedures. Alustath, 2023; 17(1): 42-49. doi: 10.37652/juaps.2023.178811

A promising strategies for reducing the danger of SARS-CoV2 transmission during dentistry and medical procedures

Journal of University of Anbar for Pure Science
Volume 17, Issue 1, June 2023, Pages 42-49    PDF (523.98 K)
Document Type: Research Paper
DOI: 10.37652/juaps.2023.178811
Authors
Waleed Khalid Mohammed* 1; Abdul Nasser H. Warwar2; Fatimah Abdulazeez Awad1
1Department of Basic Science, College of Dentistry , University Of Anbar , Ramadi, Iraq;
2College of Dentistry , University Of Anbar , Ramadi, Iraq;
Abstract
    The leaves of Stevia The COVID-19 epidemic has presented serious difficulties for healthcare professionals, especially those working in dentistry and medical facilities. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, is a high-risk infection in hospital settings since it is known to spread via respiratory droplets and aerosols. The purpose of this review paper is to determine whether preprocedural mouthwashes significantly lower the risk of SARS-CoV2 transmission during dental and medical procedures. in addition, antiseptics including Povidone-iodine, CPC, Benzalkonium Chloride, and Aromatic oils may indeed be capable of eliminating SARS-CoV2 by focusing on the virus's lipid envelope, that according in vitro study, as well as clinical experiments indicate that preprocedural mouthwashes potentially help to reduce intraoral viral load and infectivity in COVID-19 patients, but more research is required to verify this. Other infection control methods, such as PPE, high-volume evacuation (HVE), and air filtration, can also assist in minimizing SARS-CoV2 transmission during operations. The RT-qPCR alone is insufficient to determine the effectiveness of preprocedural mouthwashes against SARS-CoV2 transmission. Future research should also take into account employing supplementary techniques to evaluate the effectiveness of preprocedural mouthwashes, such as determining the virus's survival in cell cultures or using animal models to research the virus' transmission. Further research is needed to determine the best combination of infection control measures to reduce SARS-CoV2 transmission in healthcare settings, but preprocedural mouthwashes may be a simple, low-cost strategy to reduce transmission risk during dental and medical procedures, especially in high-risk patients.
Keywords
SARS-CoV2 transmission; COVID-19; Infection control; Mouthwashes
Supplementary Files
References
  1. Ludwig, S. and A. Zarbock, Coronaviruses and SARS-CoV-2: a brief overview. Anesthesia & Analgesia, 2020. 131(1): p. 93-96.
  2. Dhand, R. and J. Li, Coughs and sneezes: their role in transmission of respiratory viral infections, including SARS-CoV-2. American journal of respiratory and critical care medicine, 2020. 202(5): p. 651-659.
  3. Elhadi, M., et al., Assessment of healthcare workers’ levels of preparedness and awareness regarding COVID-19 infection in low-resource settings. The American journal of tropical medicine and hygiene, 2020. 103(2): p. 828.
  4. de Crane D’Heysselaer, S., et al., Systematic Review of the Key Factors Influencing the Indoor Airborne Spread of SARS-CoV-2. Pathogens, 2023. 12(3): p. 382.
  5. Moosavi, M.-S., P. Aminishakib, and M. Ansari, Antiviral mouthwashes: possible benefit for COVID-19 with evidence-based approach. Journal of oral microbiology, 2020. 12(1): p. 1794363.
  6. Marya, A., et al., Risk perception of SARS-CoV-2 infection and implementation of various protective measures by dentists across various countries. International Journal of Environmental Research and Public Health, 2021. 18(11): p. 5848.
  7. Seneviratne, C.J., et al., Efficacy of commercial mouth-rinses on SARS-CoV-2 viral load in saliva: randomized control trial in Singapore. Infection, 2021. 49: p. 305-311.
  8. Carrouel, F., et al., Antiviral activity of reagents in mouth rinses against SARS-CoV-2. Journal of dental research, 2021. 100(2): p. 124-132.
  9. Bai, C., Q. Zhong, and G.F. Gao, Overview of SARS-CoV-2 genome-encoded proteins. Science China Life Sciences, 2022. 65(2): p. 280-294.
  10. Gadanec, L.K., et al., Can SARS-CoV-2 virus use multiple receptors to enter host cells? International journal of molecular sciences, 2021. 22(3): p. 992.
  11. Poduri, R., G. Joshi, and G. Jagadeesh, Drugs targeting various stages of the SARS-CoV-2 life cycle: Exploring promising drugs for the treatment of Covid-19. Cellular signalling, 2020. 74: p. 109721.
  12. Choi, H., et al., Current understanding of the surface contamination and contact transmission of SARS-CoV-2 in healthcare settings. Environmental chemistry letters, 2021. 19: p. 1935-1944.
  13. Marquès, M. and J.L. Domingo, Contamination of inert surfaces by SARS-CoV-2: Persistence, stability and infectivity. A review. Environmental research, 2021. 193: p. 110559.
  14. Accorsi, E.K., et al., How to detect and reduce potential sources of biases in studies of SARS-CoV-2 and COVID-19. European Journal of Epidemiology, 2021. 36: p. 179-196.
  15. Tsuchiya, H., The Oral Cavity Potentially Serving as a Reservoir for SARS-CoV-2 but Not Necessarily Facilitating the Spread of COVID-19 in Dental Practice. European Journal of Dentistry, 2022.
  16. Chen, X., et al., The microbial coinfection in COVID-19. Applied microbiology and biotechnology, 2020. 104: p. 7777-7785.
  17. Organization, W.H., Rational use of personal protective equipment for coronavirus disease (COVID-19) and considerations during severe shortages: interim guidance, 6 April 2020. 2020, World Health Organization.
  18. Davies, K., et al., Effective in vitro inactivation of SARS-CoV-2 by commercially available mouthwashes. The Journal of general virology, 2021. 102(4).
  19. Garcia-Sanchez, A., et al., Efficacy of pre-procedural mouthwashes against SARS-CoV-2: A systematic review of randomized controlled trials. Journal of Clinical Medicine, 2022. 11(6): p. 1692.
  20. Chen, M.-H. and P.-C. Chang, The effectiveness of mouthwash against SARS-CoV-2 infection: A review of scientific and clinical evidence. Journal of the Formosan Medical Association, 2022. 121(5): p. 879-885.
  21. Silva, A., et al., The effect of mouthrinses on severe acute respiratory syndrome coronavirus 2 viral load: A systematic review. The Journal of the American Dental Association, 2022. 153(7): p. 635-648. e16.
  22. Tonkaboni, A., et al., Impact of COVID-19 on Dentistry. Coronavirus Disease-COVID-19, 2021: p. 623-636.
  23. Meister, T.L., et al., Virucidal efficacy of different oral rinses against severe acute respiratory syndrome coronavirus 2. The Journal of infectious diseases, 2020. 222(8): p. 1289-1292.
  24. Carrouel, F., et al., COVID-19: a recommendation to examine the effect of mouthrinses with β-cyclodextrin combined with citrox in preventing infection and progression. 2020, MDPI. p. 1126.
  25. Anderson, D.E., et al., Povidone-iodine demonstrates rapid in vitro virucidal activity against SARS-CoV-2, the virus causing COVID-19 disease. Infectious diseases and therapy, 2020. 9(3): p. 669-675.
  26. Eggers, M., et al., Povidone-iodine hand wash and hand rub products demonstrated excellent in vitro virucidal efficacy against Ebola virus and modified vaccinia virus Ankara, the new European test virus for enveloped viruses. BMC infectious diseases, 2015. 15: p. 1-8.
  27. Kampf, G., et al., Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents. Journal of hospital infection, 2020. 104(3): p. 246-251.
  28. Toghchi, S.G., N. Azimi, and N. Azimi, The role of preprocedural mouth rinse application in decreasing COVID-19 transmission in Dental Care Settings: A mini-review. 2022.
  29. Vasco-dos-Santos, D.R., et al., Plantas y parasitosis intestinal: una revisión sobre el uso etnofarmacológico de la comunidad indígena Kantaruré-Batida de Brasil. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, 2022. 21(3): p. 268-308.
  30. O’Donnell, V.B., et al., Potential role of oral rinses targeting the viral lipid envelope in SARS-CoV-2 infection. Function, 2020. 1(1): p. zqaa002.
  31. de Arruda, J.A.A., et al., Mouthwashes in the Era of COVID-19: an Overview of Current Evidence. ARCHIVES OF HEALTH INVESTIGATION, 2022. 11(5): p. 767-778.
  32. Lin, Q., et al., Sanitizing agents for virus inactivation and disinfection. View, 2020. 1(2): p. e16.
  33. Hernández-Vásquez, A., et al., Mouthrinses and SARS-CoV-2 viral load in saliva: a living systematic review. Evidence-Based Dentistry, 2022: p. 1-7.
  34. Reis, I.N.R., et al., Can preprocedural mouthrinses reduce SARS-CoV-2 load in dental aerosols? Medical hypotheses, 2021. 146: p. 110436.
  35. Elzein, R., et al., In vivo evaluation of the virucidal efficacy of chlorhexidine and povidone-iodine mouthwashes against salivary SARS-CoV-2. A randomized-controlled clinical trial. Journal of evidence based dental practice, 2021. 21(3): p. 101584.
  36. Cieplik, F. and N. Jakubovics, Preprocedural Mouthwashes for Reduction of SARS-CoV-2 Viral Load and Infectivity. Journal of Dental Research, 2022. 101(12): p. 1421-1423.
  37. Garcia-Sanchez, A., et al., Povidone-iodine as a pre-procedural mouthwash to reduce the salivary viral load of SARS-CoV-2: A systematic review of randomized controlled trials. International journal of environmental research and public health, 2022. 19(5): p. 2877.
  38. Maurya, R.K., et al., Povidone-iodine preprocedural rinse—An evidence-based, second-line defense against severe acute respiratory coronavirus virus 2 (SARS-CoV-2) in dental healthcare. Infection Control & Hospital Epidemiology, 2022. 43(6): p. 822-824.
  39. Ather, A., A. Parolia, and N.B. Ruparel, Efficacy of mouth rinses against SARS-CoV-2: a scoping review. Frontiers in Dental Medicine, 2021. 2: p. 648547.
  40. Takeda, R., et al., Antiviral effect of cetylpyridinium chloride in mouthwash on SARS-CoV-2. Scientific reports, 2022. 12(1): p. 14050.
  41. McCaul, L.K., Oral and dental management for head and neck cancer patients treated by chemotherapy and radiotherapy. Dental update, 2012. 39(2): p. 135-140.
  42. Ferrer, M.D., et al., Clinical evaluation of antiseptic mouth rinses to reduce salivary load of SARS-CoV-2. Scientific reports, 2021. 11(1): p. 24392.
  43. Kirby, J.E., et al., SARS-CoV-2 antigen tests predict infectivity based on viral culture: comparison of antigen, PCR viral load, and viral culture testing on a large sample cohort. Clinical Microbiology and Infection, 2023. 29(1): p. 94-100.
Statistics
Article View: 189
PDF Download: 94


Journal Management System. Powered by ejournalplus.com