Synthesis, Characterization of some new Heterocyclic Compounds Derived from Chalcones Containing Schiff Bases | ||
| Rafidain Journal of Science | ||
| Article 14, Volume 32, Issue 1, March 2023, Pages 127-137 PDF (768.63 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/rjs.2023.177295 | ||
| Authors | ||
| tharee Ghanim* 1; Adnan O. Omar2 | ||
| 1Department of Chemistry, College of Science, University of Mosul, Iraq | ||
| 2Department of Chemistry/ College of Science/ University of Mosul, Mosul-Iraq | ||
| Abstract | ||
| The present work involves the new chalcones containing Schiff bases, In this study, firstly, reaction of 3-acetylcoumarin with terephthaldehyde to prepared chalcones which contains a free aldehyde group which has been reacted with (4-Aminoantipyrine) to prepare Schiff bases, which was reacted (sodiumazide) as precursor to form (Tetrazole) followed by condensation of these chalcones with some compounds (hydroxylamine, aminophenol, phenylenediamine, hydrazine, semicar- bazide, thiosemicarbazide, urea, thiourea and quanidine) as precursor to form Isoxazole, oxazepane, diazepine, pyrazoles and pyrimidine derivatives in basic medium using classical and ultrasonic technique. The comparison of the classical methods with ultrasonic methods. Was achieved. The compositions of the prepared compounds were confirmed by FT- IR and 1H NMR spectroscopy. | ||
| Keywords | ||
| Tetrazole; Isoxazoles; Chalcones; 3- Acetylcoumarin; ultrasonic techniq | ||
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