Clinical and Biochemical Indicators with Zinc Consumption in Geriatric Patients at Geriatric Clinic in Medical City | ||
Iraqi Postgraduate Medical Journal | ||
Article 3, Volume 21, Issue 4, October 2022, Pages 383-390 PDF (398.13 K) | ||
Document Type: Research Paper | ||
DOI: 10.52573/ipmj.2021.176983 | ||
Authors | ||
Basmah M. Ali1; Zahraa Hussam Eldon Ismaeel2; Zaid Abedel-Elah Mustafa Al- Najjar3 | ||
1Consultant Specialist in Community Medicine, Medical City / Qazi Al- Harrery - Teaching Hospital, Baghdad, Iraq. | ||
2Specialist in Family Medicine, Medical City/ Baghdad- Teaching Hospital, Baghdad, Iraq. | ||
3Medical City /Iraqi Center for Heart Diseases, Baghdad, Iraq. | ||
Abstract | ||
BACKGROUND: The need of micronutrients in nutrients and human fitness is unquestionable and zinc (Zn) is a vital hint detail whose significance has been particularly outstanding in getting older, and immune senescence. Its deficiency is common within the aged and ends in numerous age-associated continual ailments together with atherosclerosis, degenerative illnesses of the fearful gadget, immunosenescence, and cancer. OBJECTIVE: The goal of this study is to estimate the ability position of the zinc supplementation in older patients whose aged 65 years and more, as a way to repair the immune reaction and the primary consequences of zinc on immune senescence with relation to gender and fitness kingdom, also to proof the history of infection by coronavirus 2 (SARS-CoV-2) among the studied sample. PATIENTS AND METHODS: This study covered 415 patients aged of 60 -89 years of both genders in a cross sectional study from January –April 2021 at geriatric health facility in Baghdad Teaching Hospital / Medical City and was classified according to usage of zinc supplement in the previous 6 months. The results of investigation were then compared to their archived data. Analytic study with the aid of using SPSS had been executed to evaluate the frequency of zinc intake in aged. The p value < 0.05 was significant. RESULTS: Among males who constitute 63.4 % of studied patients, 49.8% were using zinc in comparison with 37.5 % among females. The percentage of zinc intake as medical treatment was 62.8 % and 37.2% as a prophylaxis. CONCLUSION: The Nutritional interventions, inclusive of the supplementation of nutrients and minerals, make a contribution to latent therapeutic plan for COVID-19, appearing additionally to alter glucose and lipid level in blood. | ||
Keywords | ||
zinc supplement (Zn supplement); immunosenescence; micronutrient | ||
References | ||
10. Evans GW. Zinc and its deficiency diseases. Clin Physiol Biochem. 1986;4:94–98.
11. Genser D. Food and drug interaction: consequences for the nutrition/health status. Ann Nutr Metab. 2008;52:29–32.
12. alavolta M, Giacconi R, Piacenza F, Santarelli L, Cipriano C, Costarelli L, Tesei S, Pierpaoli S, Basso A, Galeazzi R, Lattanzio F, Mocchegiani E. Plasma copper/zinc ratio: an inflammatory/nutritional biomarker as predictor of all-cause mortality in elderly population. Biogerontology. 2010;11:309–319.
13. Mocchegiani E, Malavolta M, Lattanzio F, Piacenza F, Basso A, Abbatecola AM, Russo A, Giovannini S, Capoluongo E, Bustacchini S, Guffanti EE, Bernabei R, Landi F (2011) Cu to Zn ratio, physical function, disability, and mortality risk in older elderly (ilSIRENTE study). AGE (in press).
14. Ángel Julio Romero Cabrera Zinc, aging, and immunosenescence: an overview Pathobiol Aging Age Relat Dis. 2015; 5: 10.3402/pba.v5.25592.
15. Roohani N, Huvell R, Kelishadi R, Schulin R. Zinc and its importance for human health: an integrative review. J Res Med Sci. 2013;18:144–57.
17. .Pae M, Meydani SN, Wu D. The role of nutrition in enhancing immunity in aging. Aging Dis. 2012;3:91–129.
18. Trinch C. Immunity and nutrition. In: Morley JE, Thomas DR, editors. Geriatric nutrition. Boca Ratón. FL: CRC Press; 2007: 69–102.
20. Julie Shlisky, David E Bloom, Amy R Beaudreault, Katherine L Tucker, Heather H Keller, Yvonne Freund-Levi, Roger A Fielding, Feon W Cheng, Gordon L Jensen, Nutritional Considerations for Healthy Aging and Reduction in Age-Related Chronic Disease 2017;8:17–26.
22. Junaidah B Barnett, Maria C Dao, Davidson H Hamer, Ruth Kandel, Gary Brandeis, Dayong Wu, Gerard E Dallal, Effect of zinc supplementation on serum zinc concentration and T cell proliferation in nursing home elderly: a randomized, double-blind, placebo-controlled trial .The American Journal of Clinical Nutrition, Volume 103, Issue 3, March 2016: 942–51.
23. Fantacone ML, Lowry MB, Uesugi SL, Michels AJ, Choi J, Leonard SW, Gombart SK, Gombart JS, Bobe G, Gombart AF. The Effect of a Multivitamin and Mineral Supplement on Immune Function in Healthy Older Adults: A Double-Blind, Randomized, Controlled Trial. Nutrients. 2020;12:2447.
24. Iddir M, Brito A, Dingeo G, Fernandez Del Campo SS, Samouda H, La Frano MR, Bohn T. Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis. Nutrients. 2020;12:1562.
25. Richardson DP, Lovegrove JA. Nutritional status of micronutrients as a possible and modifiable risk factor for COVID-19: a UK perspective. Br J Nutr. 2021;125:678-84.
26. Richardson DP, Lovegrove JA. Nutritional status of micronutrients as a possible and modifiable risk factor for COVID-19: a UK perspective. Br J Nutr. 2021;125:678-84.
27. de Almeida Brasiel PG. The key role of zinc in elderly immunity: A possible approach in the COVID-19 crisis. Clin Nutr ESPEN. 2020;38:65-66.
28. Gammoh N.Z., Rink L. Zinc in Infection and Inflammation. Nutrients. 2017;6:624.
29. Ranasinghe P, Wathurapatha WS, Ishara MH, Jayawardana R, Galappatthy P, Katulanda P, Constantine GR. Effects of Zinc supplementation on serum lipids: a systematic review and meta-analysis. Nutr Metab (Lond). 2015;12:26.
30. Wang X, Wu W, Zheng W, Fang X, Chen L, Rink L, Min J, Wang F. Zinc supplementation improves glycemic control for diabetes prevention and management: a systematic review and meta-analysis of randomized controlled trials. Am J Clin Nutr. 2019; 110:76-90.
31. Yao J, Hu P, Zhang D. Associations Between Copper and Zinc and Risk of Hypertension in US Adults. Biol Trace Elem Res. 2018;186:346-53.
32. Trujillo-Mayol I, Guerra-Valle M, Casas-Forero N, Sobral MMC, Viegas O, Alarcón-Enos J, Ferreira IM, Pinho O. Western Dietary Pattern Antioxidant Intakes and Oxidative Stress: Importance During the SARS-CoV-2/COVID-19 Pandemic. Adv Nutr. 2021 Jan 13:nmaa171.
| ||
Statistics Article View: 40 PDF Download: 53 |