PREDICTORS OF EARLY AND DELAYED GRAFT FUNCTION IN LIVE AND CADAVERIC RENAL TRANSPLANTATION | ||
| Basrah Journal of Surgery | ||
| Article 2, Volume 29, Issue 1 - Serial Number 57, May and June 2023, Pages 4-14 PDF (416.16 K) | ||
| Document Type: Original Article | ||
| DOI: 10.33762/bsurg.2022.135361.1029 | ||
| Authors | ||
| SUNIL SATIHAL1; Sandeep Kumar Reddy2; Ifrah Ahmad Qazi* 3; RAHUL DEVRAJ4; DHEERAJ SSS5 | ||
| 1Department of Urology, Nizam’s Institute of Medical Sciences | ||
| 2Department Of Urology, Narayana Medical College, Nellore | ||
| 3Department of Urology, Narayana Medical College, Nellore | ||
| 4Department of Urology, Nizam’s Institute of Medical Sciences , Hyderabad | ||
| 5Department of Urology, Nizam’s Institute of Medical Sciences , Hyderabad , Telangana ,India. | ||
| Abstract | ||
| Background: Kidney transplantation gives the best quality of life to chronic kidney disease patients and also increases longevity. Aim: Analysis of factors responsible for the early and delayed graft functioning in live and cadaver renal transplants Methods: It was a retrospective observational study. Donor and recipient age, sex, BMI, comorbid illness, and functioning status of the donor kidney, duration and severity of chronic kidney disease and associated bladder disorders were collected. Operative factors like perfusion time, cold ischemia time, blood pressure fall, need for blood transfusion, vasopressor support was recorded. Patients were divided into two groups based on early versus delayed graft function. Results: 27 cases of Live donor renal transplant and 23 cadaver transplants were included. The average age in live donor and cadaveric transplants was 43.5 ±7.6 years and 38.3 ±10.5 years, respectively. 24 Live Transplant Recipients had Early Graft function (89%). Seven Cadaveric Transplant Recipients had Early Graft function (31%) and 16 of them had Delayed Graft Function (69%). HLA Mismatch, Perioperative Hypotension and BMI of recipient had statistically significant relationship to Early Graft Function with p values of 0.02, 0.004 and 0.007, respectively. With p-value of 0.021 and of 0.046, respectively, perioperative hypotension and cold ischemic time in Cadaveric renal transplantation had statistically significant relationship to Early Graft Function. Conclusion: Live donor transplants have better early graft function. HLA Mismatch, Perioperative Hypotension, BMI of recipient and cold ischemic time in Cadaveric renal transplantation are the predictors of early graft function. | ||
| Keywords | ||
| Cadaveric,,; ,،,؛Kidney transplantation,,; ,،,؛Early Graft Function | ||
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