Alsudani, R., Al- Hayali, A. (2021). Transdermal Scopolamine Alternative to Ondansetron for Prevention of Early 6 Hours Postoperative Laparoscopic Cholecystectomy Emetic Symptoms. Alustath, 21(3), 306-310. doi: 10.52573/ipmj.2021.175793
Raghad Hannon Alsudani; Asmaa Khalid Al- Hayali. "Transdermal Scopolamine Alternative to Ondansetron for Prevention of Early 6 Hours Postoperative Laparoscopic Cholecystectomy Emetic Symptoms". Alustath, 21, 3, 2021, 306-310. doi: 10.52573/ipmj.2021.175793
Alsudani, R., Al- Hayali, A. (2021). 'Transdermal Scopolamine Alternative to Ondansetron for Prevention of Early 6 Hours Postoperative Laparoscopic Cholecystectomy Emetic Symptoms', Alustath, 21(3), pp. 306-310. doi: 10.52573/ipmj.2021.175793
Alsudani, R., Al- Hayali, A. Transdermal Scopolamine Alternative to Ondansetron for Prevention of Early 6 Hours Postoperative Laparoscopic Cholecystectomy Emetic Symptoms. Alustath, 2021; 21(3): 306-310. doi: 10.52573/ipmj.2021.175793

Transdermal Scopolamine Alternative to Ondansetron for Prevention of Early 6 Hours Postoperative Laparoscopic Cholecystectomy Emetic Symptoms

Iraqi Postgraduate Medical Journal
Article 9, Volume 21, Issue 3, July 2022, Pages 306-310    PDF (183.24 K)
Document Type: Research Paper
DOI: 10.52573/ipmj.2021.175793
Authors
Raghad Hannon Alsudani1; Asmaa Khalid Al- Hayali2
1Baghdad Medical City, Baghdad, Iraq
2Al-Karma Maternity and Emergency Hospital, Al-Anbar, Iraq
Abstract
BACKGROUND:
Nausea and vomiting are the commonest complication Post-operatively which are usually                         self-limiting; however, it can cause serious consequences. There are many drugs to manage                       Post-operative nausea and vomiting.
OBJECTIVE:
Compare the efficacy of transdermal scopolamine versus ondansetron for the prevention of                         post-operative laparoscopic cholecystectomy emetic symptoms.
PATIENTS AND METHODS:
One hundred patients who were candidate for undergoing laparoscopic cholecystectomy are divided in to two groups each of them have 50 patients, first group received an active TDS patch  (containing scopolamine 1.5 mg) 60 min before entering the operating room. The second group was administered ondansetron, 4 mg that was administered I.V near the end of the procedure, and all patients received                a standardized general anesthetic technique.
RESULTS:
There were no significant differences in any of the emetic outcomes orneed for rescue antiemetics between TDS and ondansetron groups inthe first 6 h after surgery.
CONCLUSION:
Premedication with TDS (1.5) mg was as effective as ondansetron (4 mg) in preventing nausea and vomiting in the early postoperative periods. Also less cost with TDS patch.
 
Keywords
transdermal scopolamine; ondansetron; nausea and vomiting, antiemetic
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