Study the Growth of Apatite Layer on Biodegradable Glass as Bioactive Scaffolds

Dhary, Zainab I.; Atiyah, Alaa A.; Farid, Saad B. H.

doi:10.30684/etj.2021.131678.1048

	Study the Growth of Apatite Layer on Biodegradable Glass as Bioactive Scaffolds
Engineering and Technology Journal
Article 8, Volume 40, Issue 6, June 2022, Pages 892-900 PDF (1.5 M)
Document Type: Research Paper
DOI: 10.30684/etj.2021.131678.1048
Authors
Zainab I. Dhary^* ¹; Alaa A. Atiyah²; Saad B. H. Farid¹
¹Materials Engineering Dept, University of Technology-Iraq, Alsina’a Street, 10066 Baghdad, Iraq.
²Materials Engineering Dept, University of Technology-Iraq, Alsina’a Street, 10066 Baghdad, Iraq
Abstract
Bioglass offers a variety of uses for tissue engineering due to its good biocompatibility and chemical composition, similar to a mineral portion of the body. The synthesis of bioglass 13-93 scaffold was achieved by salt leaching technique, and potassium chloride (KCl) was used as porogen with particle sizes of (200-250) μm. Then, sintering to 750 ◦C for around 1 hour was performed. The resultant materials were examined by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and scanning electron microscopy (SEM). They were immersed in a solution of simulated body fluids (SBF) for 7 and 14 days, respectively. Initially, calcium phosphate was created. After 7 and 14 days, the surface comprised of developed crystalline apatite. The bioactivity of scaffolds that were created and examined. The FTIR, SEM, and XRD experiments were done before and after immersion of the sample in SBF. The results showed that the scaffolds contained open and interconnected pores with porosities ranging between (75-78%). The maximum value of compressive strength of the prepared scaffold was about 5.6MPa. Based on the obtained results, the glass scaffolds can be considered promising for bone defects and replacement applications
Highlights
The maximum compressive strength of the bioglass scaffold was found to be about 5.6MPa. The prepared scaffold of bioglass has open porosity and interconnection ranging from about 75 to 78 %. The glass scaffolds can be considered promising for bone defects and replacement applications.
Keywords
Bioglass 13-93; bioactivity; bone regeneration; Scaffold; porosity

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