A Clinical and Histopathological Study of Skin Cancer in Patients At Al-Kindy Teaching Hospital | ||
Iraqi Postgraduate Medical Journal | ||
Article 2, Volume 20, Issue 3, July 2021, Pages 213-220 PDF (312.13 K) | ||
Document Type: Research Paper | ||
DOI: 10.52573/ipmj.2020.169709 | ||
Authors | ||
Hyam Raouf Al-Hamamy; Rania Haider Faiz; Saja Haleem Shaker; Tabark Adnan Yousif | ||
Al-Kindy College of Medicine, Baghdad University, Iraq. | ||
Abstract | ||
BACKGROUND: Skin cancer is an uncontrolled skin cell growth. It most often forms on regions of the skin that are exposed to the rays of the sun. Skin cancer impacts people of all colors and races although there is a higher risk for those with fair skin who develop quick sun burns. Basal cell carcinoma, squamous cell carcinoma, and melanoma are three major types. STUDY OBJECTIVE: To study the outcomes of histopathological analysis of skin biopsies and their correlation with age, patient gender and frequency of the three types of skin cancer. PATIENTS AND PROCEDURES: A Retrospective cross sectional study was carried out in the Al-Kindy teaching hospital's clinical laboratory. In this study, surgical specimens of skin lesions that were collected from 2015 through 2018 by open biopsy of all patients were selected. Seventy cases of 39 female and 31 male patients have been reviewed. RESULTS: Out of 70 sample of skin biopsies, female percentage was 55.71% (no:39), while male percentage was 44.29% (no:31). The commonest type of skin cancer was basal cell carcinoma (68.6%) followed by squamous cell carcinoma (22.9%), followed by melanoma (8.6%). The peak incidence of BCC was at age 50-59 yrs. & 60-69 yrs. The peak incidence of SCC was at age 60-69 yrs. While melanoma occur in different groups of age mostly in 30-39 and 60-69 years age group. The peak incidence of BCC and SCC was at year 2016. CONCLUSION: Skin cancer is more in female than male and more at age 50-70 year. The commonest type of skin cancer was BCC followed by SCC followed by melanoma. | ||
Keywords | ||
Skin Cancer; Melanoma; Basal cell carcinoma | ||
References | ||
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4. Macbeth AE, Grindlay DJ and Williams HC. What's new in skin cancer. Clin Exp Dermatol. 2011; 36:453–58. 5. Samarasinghe V, Madan V and Lear JT. Management of high-risk squamous cell carcinoma of the skin. Expert Rev Anticancer Ther. 2011; 11:763–69. 6. Schulze HJ, Cribier B, Requena L, Reifenberger J, Ferrándiz C, Garcia Diez A, et al. Imiquimod 5% cream for the treatment of superficial basal cell carcinoma. Br J Dermatol. 2005; 152:939–47. 7. Kricker A, Armstrong BK, English DR and Heenan PJ. Does intermittent sun exposure cause basal cell carcinoma. A case-control study in Western Australia. Int J Cancer. 1995; 60:489–94. 8. Rosso S, Zanetti R, Martinez C, Tormo MJ, Schraub S, Sancho-Garnier H, et al. The multicentre south European study ‘Helios’. II: Different sun exposure patterns in the etiology of basal cell and squamous cell carcinomas of the skin. Br J Cancer. 1996; 73:1447–54. 9. Zak-Prelich M, Narbutt J and Sysa-Jedrzejowska A. Environmental risk factors predisposing to the development of basal cell carcinoma. Dermatol Surg. 2004; 30:248–52. 10. Situm M, Buljan M, Bulat V, Lugovic Mihic L, Bolanca Z and Simic D. The role of UV radiation in the development of Basal cell carcinoma. Coll AntropoL. 2008; 32 :167-70. 11. Smeets NW, Kuijpers DI, Nelemans P, Ostertag JU, Verhaegh ME, Krekels GA, et al. Mohs’ micrographic surgery for treatment of basal cell carcinoma of the face–results of a retrospective study and review of the literature. Br J Dermatol. 2004; 151:141–47. 12. Rubin AL , Chen EH and Ratner D. Basal cell carcinoma. N Engl J Med. 2005; 353:2262-69. 13. Rogers HW, Weinstock MA, Harris AR, et al. “Incidence estimate of nonmelanoma skin cancer in the United States, 2006. Arch Dermatol . 2010;146:283-87. 14. Weinberg A.S., Ogle C.A. and Shim E.K. Metastatic cutaneous squamous cell carcinoma: an update. Dermatologic surgery. 2007; 33: 885-99.
15. Grossman D and Leffell DJ. Squamous cell carcinoma. in: Wolff K et al (ed). Fitzpatrick’s Dermatology in General Medicine. Seventh edition. USA: McGraw Hill Medical; 2008: 1028-36. 16. Rigel DS. Epidermiology of melanoma. Semin Cutan Med surg. 2010; 4:204-9. 17. Meyle KD and Guldberg P. Genetic risk factors for melanoma. Hum Genet .2009; 4:499-510. 18. Armstrong BK and Kricker A. How much melanoma is caused by sun exposure?. Melanoma Res.1993; 3:395-401. 19. William, James, Timothy, Berger and Elston . Dermal and Subcutaneous Tumors .in : William, James, Timothy, Berger, Dirk Elston (ed) . Andrews' Diseases of the Skin: Clinical Dermatology. Eleventh edition.UK: Elsevier Inc; 2011: 1218-350. 20. Oberyszyn TM. Non-melanoma skin cancer: importance of gender, immunosuppressive status and vit D .Cancer Lett. 2008; 261: 127-36. 21. Hussein MR. Skin cancer in Egypt: a word in your ear. Cancer Biol Ther. 2005;4:593-95. 22. Bahamdan KA and Morad NA. Pattern of malignant skin tumors in Asir region, Saudi Arabia. Ann Saudi Med 1993; 13: 402- 6. 23. Hille J and Johnson NW. "The burden of oral cancer in sub-Saharan Africa: An estimate as presented to the Global Oral Cancer Forum, March 2016. Traslational Research in Oral Oncology. 2017; 2:1-13. 24. Humadi AF, Kadhim MJ and Al-Rawi JR. "Skin Cancers in Baghdad Hospitals. Iraqi Journal of Community Medicine. 2013; 26: 99-102. 25. Al Aboud KM, Al Hawsawi KA, Bhat MA, et al. "Skin cancers in Western Saudi Arabia. Saudi Med J. 2003; 24: 1381-87.
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