Efficacy of Urine Cytology in the Detection of Bladder Urothelial Carcinoma: A Retrospective Study in Medical City-Baghdad | ||
| Annals of the College of Medicine, Mosul | ||
| Article 2, Volume 43, Issue 1, June 2021, Pages 10-15 PDF (542.15 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/mmed.2021.129565.1078 | ||
| Authors | ||
| Arwa Albarhawi* 1; Professor Muhsin Sahib2 | ||
| 1Department of Pathology, Nineveh medical college, Nineveh University, Mosul, Iraq. | ||
| 2Chairman of the scientific council of the Arab Board / Pathology in Iraq. | ||
| Abstract | ||
| Abstract Objective: To make a cyto-histological correlation and to evaluate the diagnostic efficacy of urine cytology in routine practice. Materials & methods: From January 2015 to June 2020, one hundred and thirty-nine cases have been included in this case series retrospective study. Subjects were collected from the Ghazi al-Hariri Surgical Specialties Hospital, Medical City, Baghdad, Iraq. Ranging in age from fourteen to eighty-six years, presented most frequently with hematuria, or diagnosed radiologically with bladder tumor, who underwent cytological examination with the histological examination at the same time or within one year. Results: Patients were mostly between sixty-one and seventy years old (36.7%). The studied group was made of male (61.2%) and female (38.8 %). Fifty-five patients who were diagnosed as negative/ benign in cytology examination, and histological examination at the same time, eight patients were diagnosed as high-grade urothelial carcinoma when they were diagnosed negative/ benign in the cytological examination, four patients were diagnosed negative in the histological examination when they were reported as high-grade urothelial carcinoma in the cytological exam, thirty-four patients were reported as high-grade urothelial carcinoma, cytologically and histologically. The sensitivity of high-grade urothelial carcinoma detection in suspicious or malignant cases in urine cytology was (80.95%), while the specificity (92.98%). the positive predictive value was (89.47%) when the negative predictive value was (86.88%). Conclusion: It has always been known that urine cytology is a powerful and effective method for the screening of urothelial carcinoma; specifically, for high-grade urothelial carcinoma, and in the follow-up of patients after surgery or cystoscopy. | ||
| Keywords | ||
| urine; ؛cytology; ؛urothelial carcinoma screening; ؛histology; ؛; ،; ؛cystoscopy | ||
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