The Effect of Chlorohexidine Gel Foam on the Salivary Tumor Necrosis Factor and Interleukine-6 after Extraction of lower Third Molar | ||
| Al-Rafidain Dental Journal | ||
| Article 4, Volume 21, Issue 1, March 2021, Pages 35-41 PDF (356.06 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/rden.2020.128172.1050 | ||
| Authors | ||
| Dhafar mekdad .Abdul Fatah1; Maha Talal Al saffar* 2 | ||
| 1pharmesist at Abn AI-Atheer Hospital M.B.CH | ||
| 2Department of dental basic science | ||
| Abstract | ||
| Aim: This is study aimes to demonstrate the effect of chlorohexidine gelfoam on the salivary Tumor Necrosis factor and Interleukin-6 after extraction of lower third molar to compare these effect before and after extraction ' and to know the benefit of using chlorhexidine gelfoam after extraction of lower third molar . Material and method:-twenty four patients were involved, patients classified into group 1[control group],group 2 [chlorhexidine group] saliva was taken from all patients by using salivette before extraction and seven day after extraction then measure TNF andIL-6 by using [ELISA] kits' Results:- there is significance difference in (IL-6) after one week of extraction without treatment from the baseline (before extraction) and the result respectively was (1.96±0.51),( 6.20±5.22),and the result of (TNF-α) appeared no significance difference before and after treated the result after treatment is(25.9±30.8) and before treatment is (95.2±131.6) and the result of group used chlorhexidine gelfoam show significance difference in both (IL-6, TNF-α) after and before treatment, the result of IL-6 after treatment is (16.99±13.31) and before treatment is (1.57±0.18) and the result of (TNF-α) after treatment is (56±79.3) and before treatment is (102.9±133.3) Conclusion:- the use of chlorohexidine gelfoam after extraction help to decrease the salivary TNF-α. with significant difference and decrease level of IL-6 with a significant differences compare it with control group which enhance healing process and decrease the chance of infection. | ||
| Keywords | ||
| chlorohexidine gelfoam; patient with extraction; salivary (IL-6 and TNF-α) | ||
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