The effect of different vasoconstrictor containing local anaesthetic solutions on plasma glucose in normal and diabetic-volunteers | ||
| Al-Rafidain Dental Journal | ||
| Article 15, Volume 2, Issue 1, January 2002, Pages 112-119 PDF (2.43 M) | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/rden.2002.165924 | ||
| Authors | ||
| Muhammed KH HASOUNE; Faiz A AL-SULTAN | ||
| Abstract | ||
In this study, the change in plasma glucose half an hour after injection of different vasoconstrictors contained in local anaestheticsolution where measured both in normal and diabetic volunteers. Single cartridge contain (1.8) ml of plain (2%) Xylocain or that with (1:80000) concentration of a adrenaline or (3%) prilocain with (0.03) IU of felypressin injected at labial to left maxillary lateral incisor region. The result showed that half an hour after injection of a adrenaline containing solution, a very highly significant increase in plasma glucose noticed in both study groups from pre-injection base line value (p<0.001). Increase in plasma glucose in diabetic group were significantly greater than that in normal control group (p<0.05). Within diabetic volunteers, this increase were significantly greater in insulin dependent diabetic group than that in non insulin dependent volunteers. After injection of plain solution or that containing felypressin, reduction in plasma glucose noticed. In conclusion, adrenaline contained within local anaesthetic solution produce hyperglycemic effect even in dose of single dental cartridge. This response enhanced in diabetic patient in general with greater enhancement noticed in insulin dependent patient. | ||
| Keywords | ||
| diabetes; -- vasoconstrictor; -- local anesthesia | ||
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