Investigation of some bioactive compounds in oil and ethanol extracts of ginger (Zingerbiene officlica) using GC-MS | ||
| Iraqi Journal of Pharmacy | ||
| Article 2, Volume 16, Issue 1, July 2019, Pages 22-35 PDF (726.44 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/iphr.2019.165707 | ||
| Authors | ||
| Faris T. Abachi1; Khadeeja Younus2; Inas Hazim2 | ||
| 1College of Pharmacy, University of Mosul | ||
| 21Department of Pharmacognosy, 2Department of Pharmaceutical Chemistry, College of Pharmacy | ||
| Abstract | ||
| Objective: The molecular characterization of some bioactive compounds in ginger interest because of their various pharmacological activities. To the best of our knowledge, we are isolate hydrocarbon (low molecular weight), alcohol, phenol, acid, ester from nonpolar (oil) and polar (ethanol) extracts using gas chromatography-mass spectrometry [GC-MS] technique. Methods: Gas chromatography-mass spectrometry (GC-MS) analysis of the oil and ethanol extracts of ginger was carried out by using a GC-MS equipment. Results: The GC-MS analysis has revealed the existence of different bioactive chemical compounds in the oil & ethanolic extracts of ginger. The major compounds of oil extract are beta-elemene (0.27%), curcumen (3.12%), zingerberene (10.86%) , bisabolene(3.75) , elemol(1.14%), germacrene( 0.23%) , 7-epi trans sesquisabinene (1.82%), zingerberone (35.92%), ethyl palmitate (0.53%), pardol(3.97%). A total of 53 compounds identified representing of total ginger oil extract. While, the major compounds of ethanolic extract are elmene (0.51%), zingerbiene (4.43%), alloaromadentrene (0.42%), curcumene(21.83%), gama cadienene(3.24%)8-epi-.gama.-eudesmol( 0.34). A total of 50 compounds identified representing 99.98% of total ginger ethanolic extract. Conclusion: In this study, successful identification some of important bioactive compounds using GC-MS technique. | ||
| Keywords | ||
| ginger; Ethanol extract; GC-MS technique; zingeriberene; curcumene | ||
|
Statistics Article View: 368 PDF Download: 339 |
||