TAUTOMERIC TRANSITIONS WITH PHOTO-INDUCED EFFECTS USING LASER BEAM OBSERVED IN ANTIBIOTIC ERYTHROMYCIN - ESTOLATE | ||
Journal of University of Anbar for Pure Science | ||
Article 5, Volume 2, Issue 3, December 2008, Pages 14-23 PDF (822.67 K) | ||
Document Type: Research Paper | ||
DOI: 10.37652/juaps.2008.15639 | ||
Authors | ||
Hussien Ali1; Yusra M. Al-Obadi2; Ismail K. Al-Khateeb* 2 | ||
1Laser and plasma institute, Baghdad University | ||
2College of Science, University of Anbar. | ||
Abstract | ||
:The photo transitions of Erythromycin 2-propionate dodecyl sulphate (C40H71NO14, C12H26O4S) using Nitrogen Laser beam have been studied at different periods of time. Different techniques have been used to analyze and identify final products. The results showed that photo transitions of Erythromycin - Estolate which measured by conductivity initially increased and then decreased with time especially at high pulse rate. While pH showed a different behavior and initially there was reduction in pH values by increasing the pulse rate. The kinetic study indicated that the rate of reaction is of the second-order type . The qualitative identification showed that the final products were; • First: 6-(4-Dimethylamino-3-O-propionyl –6-methyl- tetrahydro-pyran-2-yloxy)-14-ethyl-4-(5-hydroxy-4-methoxy-4,6-dimethy-tetrahydro-pyran-2-yloxy)-3,5,7,9,11,13-hexamethyl-oxacyclotetradeca-2,10-dione-7,12,13-propaniol dodecyl sulphate.• Second: 6-(4-Dimethylamino-3-O-propionyl –6-methyl- tetrahydro-pyran-2-yloxy)-14-ethyl-4-(5-hydroxy-4-methoxy-4,6-dimethy-tetrahydro-pyran-2-yloxy)-3,5,7,9,11,13-hexamethyl-oxacyclotetradeca-2,9-diene-2,7,10,12,13-pentaol dodecyl sulphate. The final products showed an existaence of enol group through a tautomerism reaction of keto enol. | ||
Keywords | ||
Tautomeric transitions; Erythromycin; Estolate; Laser | ||
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