THE EFFECT OF LICORICE EXTRACT ON SOME PHYSIOLOGICAL TRAITS IN WHITE SWISS MICE | ||
| Journal of University of Anbar for Pure Science | ||
| Article 13, Volume 3, Issue 2, August 2009, Pages 47-51 PDF (543.81 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.37652/juaps.2009.15477 | ||
| Author | ||
| NIDHAL IBRAHIM LATEFF* | ||
| Anbar University - College of Science | ||
| Abstract | ||
| This study was conducted to know the effect of licorice on physiological traits in mice This include the concentration of enzymes for the group, which included both the (GOT) and (GPT) for each of the liver, heart, kidney and spleen when given doses of the extract of different Licorice. In this study white Swiss mice of 30 days old were used. the animals were divided into four groups (6 animals each group) and by the concentration in addition to the abstract where the control group was given three different concentration of licorice extract (0.0002) g / day (0.0004) g / day (0.0006) g / day for four weeks while the control group was saline solution. The animals were weighted and dissected , after then the (liver, heart, spleen and kidney) were estimated their enzymatic concentration of( GOT and GPT) by spectrophotometer.The result of this study showed that there was a gradual increase in the body weight with the increase of the dosages of the extract of the licorice.The results of this study showed that there are on effective "non-moral" of the licorice extract on the enzyme GOT and GPT of the liver at the level of probability (P> 0.05), but this was a moral influence "clear" each of the total enzyme, heart and spleen and at the level of probability (P extract, compared with a control. | ||
| References | ||
|
1- Olukoga A, Donaldson D. Historical perspectives on health . The history of licquorice ; the plant , its extract , cultivation ,and commercialization and etymology . JRSoc Health 1998 ; 118: 300 – 304 .
2-Ploeger B , Mensinga T, Sips A , et al The pharmacokinetics of glycyrrhizic acid evaluated by phtsiologically based pharmacokinetic modeling . Drug Metab Rev 2001 ; 33 : 125 – 147 .
3- موسى ، طارق ناصر ، عبد الجبار وهیب الحدیثی ، عبد المجید ناصر ( 2003 ) .تقدیر مستوى بعض المکونات الغذائیة والعناصر المعدنیة لمسحوق جذور نبات عرق السوس المحلی Glycyrrhiza glabra ، مجلة العلوم الزراعیة العراقیة ، 34 (2) ، 19 – 26 . 4- Cinatl J. Morgenstern B. Baner G , etal .Glycyrrhizin an active component of licquorice roots and replication of SARS associated . coronavirus lancer 2003 ; 36 (9374 ) : 2045 – 2046.
5- Fujioka T . Kondou T .Fukuhara A . etal . Efficacy of glycyrrhizin suppository for the treatment of chronic hepatitis C: apilot study . Hepatol Res 2003; 26 (1) : 10 – 14
6- Tamir S , Eizenberg M, Somjen D, etal . Estrogenic and antiproliferative properties of glabridin from licorice in human breast cancer cells. Cancer Res 2000 ; 60 : 5704 – 5709 .
7-Kamej . J , Nakamura R , Ichiki H etal . Tutitussive principles of glycyrrizae radix amain component of the kampo preparations bakumondo – to (Mai - men –dongtang ). Eurj pharmacol 2003; 469 (1-3) : 159 -163 .
8 – British Herbal Pharmacopeia . (1983). Published dy the British Herbal Association . 25 : 77 -80
9-Danial , W. W. (1999) . Biostatistics : Afoundation for analysis in the health Sciences . 7th Ed . , Fohn Wiley & Sons , inc . New York . .
10- الخزرجی، عبد الجبار عبد الحمید ، عادل محسن نذیر الجنابی ، سعدی شعلان خلف ، خضیر عباس محمد ومحمود محمد علی (2006). تاثیر احلال نسب من مخلفات عرق السوس عن الشعیر فی علائق التسمین على بعض الصفات الدمویة والکیمیاحیویة لعجول الفریزیان ، مجلة العلوم الزراعیة العراقیة ، 34 (1) ، 20 – 29. 11 – Goso Y , OgataY , Ishihara K, Hotta K . Effects of traditional herbal medicine on gastric mucin against ethanol – induced gastric injury in rats . Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 1996 ; 113 : 17 – 21 .
12- بهجت، احسان محمد وعزیز موسى شعبان. (1985). الکیمیاء السریریة. وزارة التعلیم العالی والبحث العلمی. 13- Van RoossumTG, Vulto AG, Hop WC , Schalm SW.Glycyrrhizin – induced reduction of ALT inEuropean patients with chronic hepatitis C. Am J Gastroenterol 2001 ; 96 : 2432 – 2437 .
14 – Anon , 2005 . Glycyrrhiza glabra . Alternative Medicine Review 10 , 230 – 237 . | ||
|
Statistics Article View: 80 PDF Download: 78 |
||