SYNTHESIS A NUMBER OF URIDINE DERIVATIVES AND STUDYING THEIR BIOLOGICAL ACTIVITY ON PATHOGENIC BACTERIA. | ||
| Journal of University of Anbar for Pure Science | ||
| Article 12, Volume 5, Issue 1, April 2011, Pages 38-43 PDF (499.89 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.37652/juaps.2011.15472 | ||
| Authors | ||
| YOUSIF HINDY KHALAF* 1; SALMAN ALI AHMED2 | ||
| 1College of Science - Anbar University | ||
| 2Al-Nahrain University - College of Science | ||
| Abstract | ||
| یتضمن البحث تحضیر سلسلة من المرکبات بطریقة ازدواج املاح الدیازونیوم مع الیوردین. وتم التأکد من الصیغ الترکیبیة للمرکبات المحضرة بدراسة اطیاف الاشعة فوق البنفسجیة (U.V) واطیاف الاشعة تحت الحمراء(I.R) والتحلیل الدقیق لعناصر الکاربون، الهیدروجین والنتروجین (C.H.N) وتضمن البحث ایضاً دراسة الفعالیة البایولوجیة لهذه المرکبات على خمسة اجناس من البکتریة المرضیة: S. aureus , Str. viridians, Ps. aeruginosa , E. coli and Sh. Dysenteriae وبأستخدام طریقة نشر الاقراص ووجد ان لهذه المرکبات تأثیر متوسط فی تثبیط هذه الاجناس من البکتیریا. | ||
| Keywords | ||
| Uridine; Azo; synthesis; biological activity; bacteria | ||
| References | ||
|
[1] J. Arts and M. Wainberg, Amer. Soc. for Microbiology, (1996) 40, 527.
[2] C. Perigand, G. Gosselin and J. L. Imbach, Nucleoside and Nucleotides, (1992) 11, 914.
[3] B. Foth., Cancer Res., (1972)32, 804.
[4] F. A. French and E. Blanz, Cancer Res. (1965)25, 1454.
[5] A. C. Sartorelli, K. C. Agrawal and E. C. Moore, Biochem. Pharmaco., (1971) 20 ,3199.
[6] V. Betiana, “The Chemistry and Biology of Antibiotic”, Elsevier Scientific Publishing Comp. Amsterdam, (1983) 283.
[7] Wilson and Givolds, Text Book of Organic Medical and Pharmaceutical Chemistry 10th ed. (1988).
[8] A. Kalski, H. Strozynski and W. Smok, Med-Pr. (1994) 45(2), 107.
[9] Franklin and Snow, “Biochemistry of Antimicrobial Action”, 4th ed. (1987) 106.
[10] H.Abid, Ph.D.''Thess Univ. of babilon, Iraq (2003).
[11] H. W. Seely, Jr., P. J. Vandemark, “Microbes in Action”, 3rd. ed., W. H. Freedman and Comp. (1981) 178.
[12] R. M. Silverstein, G. C. Bassler and T.C. Morrill, “Spectrometric Identification of Organic Compounds”, 4th. ed., John Wiley and Son New York (1988).
[13] V. M. Parikn, “Absorption Spectroscopy of Organic Molecules”, (Arabic Translation) A. H. Khuthier and J. M. Al-Rawi, University of Mosul (1985).
[14] R. L. Pecsok and Shields, “Modern Methods of Chemical Analysis”, 2nd. ed. (Arabic Translation) M. A. Mahdi, Mellitary Engineering College (1988).
[15] W. Kemp, “Organic Spectroscopy”, The macmillan Press LTD (1975) 47.
[16] M. Siroki; J. Less – common metals, (1971) 25 , 431.
[17] L. J. Bellamy, “The Infrared Spectra of Complex Molecules”, Printed in Great Britain By Low. Brydon, LTD (1975).
[18] K. Luttke and W. Zeit; Electro chem., (1960) 64, 650.
[19] K. Ueno; J. Amer. Chem. Soc., (1957) 79, 3066.
[20] D. J. Hadzi; J. Chem. Soc., (1956) 2143. | ||
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