Effect of Aquatic and Alcoholic Extracts Nigella sativa Seeds on Glucose and Lipid Profile in the Blood of Males Albino Rats Rattus norvegicus. | ||
Journal of Tikrit University For Agriculture Sciences | ||
Article 1, Volume 18, Issue 3, December 2018, Pages 43-49 | ||
Author | ||
Adnan Mohammed Ahmeed Aldulaimi | ||
Abstract | ||
The study carried out to investigate the effect of orally feeding from each Nigella sativa aqueous and alcoholic extracts at 50 and 100 mg/kg concentration of animal body weight lipid profile and Glucose parameters in male rats for 21 days. Randomly divided in to (5) groups, each group included (5) animals. The results showed a sinificant decrease (p<0.05) in cholesterol, triglycerides, LDL-C, VLDL-C, Glucose levels and significant increase (p<0.05) in HDL-C level, with the increased concentration of aqueous extract, when compared with the same values in control group. While orally feeding with The alcoholic extract at 50 and 100 mg/g concentration, led to a significant decrease (p<0.05) in concentrations of cholesterol, triglycerides, LDL-C, VLDL-C, Glucose and significant increase (p<0.05) in HDL-C levels, with the increased concentration of extract, when compared with the same values in control group. The study concluded that, the Nigella sativa aqueous extracts greater effect than the alcoholic extracts in decreased lipid profile and Glucose parameters in male rats. | ||
Keywords | ||
Nigella sativa aquatic and alcoholic extracts; Glucose; Lipid profile | ||
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