Effect of Midazolam on Heart Rate in Pediatric Anesthesia | ||
| Iraqi Postgraduate Medical Journal | ||
| Article 1, Volume 15, Issue 4, December 2016, Pages 441-445 PDF (0 K) | ||
| Author | ||
| Sanaa Fareed Qassim | ||
| Abstract | ||
| ABSTRACT: BACKGROUND : Midazolam is one of benzodiazepines. It is most lipid soluble as a result has a rapid onset and short duration of action, used in anesthesia for sedation or intravenous induction according to the dose used. OBJECTIVE: Is to notice if there is an effect of midazolam on heart rate in pediatric patients with using ketamine as induction agent under general anesthesia. PATIENTS AND METHODS: 60 peadiatric patients undergoing surgery randomly allocated in 2 groups(A and B). Aneasthesia was standardized for all patients (except addition of Midazolam in sedative dose (0.03 mg/kg) i.v. preinduction to group( B). Heart rate measured preoperatively as abaseline and 5 and 15 minutes after induction. RESULTS: Adding midazolam associated with a reduction in HR by an average of 10 beats/min 5 and 15 minutes after induction of anaesthesia. This effect failed to reach the level of statistical significance although it was clinically significant. CONCLUSION: Midazolam have well known sedative effect but have no significant effect on heart rate in paediatric patients. | ||
| Keywords | ||
| KEYWORDS; heart rate; ketamine | ||
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