The Frequency of Autonomic Neuropathy in Type 2 Diabetic Patients | ||
| Iraqi Postgraduate Medical Journal | ||
| Article 1, Volume 15, Issue 2, June 2016, Pages 127-131 PDF (0 K) | ||
| Authors | ||
| Asaad Abdullah Abbas; Abbas K. Ressan; Ali HAshim Hussein | ||
| Abstract | ||
| Abbas K. Ressan, Asaad Abdullah Abbas,Ali HAshim Hussein INTRODUCTION: Autonomic nervous system (ANS) The ANS supplies and influences every organ in the body and closely integrate vital processes, such as Blood Pressure (BP), temperature and adaptation to environmental change (1). Accordingly, sensory, motor, visceral and neuroendocrine function can be modulated by this system (2). Baghdad Teaching Hospital. The clinical signs and symptoms that occur in disturbances of autonomic response which is influenced by the organ involved. The normal balance of sympathetic (ST) and parasympathetic (pst) innervations, the nature of underlying illness and stage of progression of the disease (3). To investigate the prevalence of D.A.N. was defined by simple non- invasive tests in type 2 diabetic Iraqi patients and it is relation to the duration of the disease. ABSTACT: BACKGROUND: Autonomic Nervous System Innervates vascular and visceral smooth muscle, exocrine and endocrine glands and parenchymal cells through out the various organ system. Diabetic autonomic neuropathy is classified as subclinical or clinical upon the presence or absence of symptoms Awide spectrum of symptoms affecting many different organ system can occur including CVS, GUS, pupillary, automotor and neuroendocrine systems. OBJECTIVE: To investigate the frequency of diabetic A.N.P as defined by simple non – invasive test in type 2 diabetic Iraqi patients and it is relation to the duration of disease. PATIENTS AND METHODS: Fifty type 2 diabetic patients , were evaluated with a five bed side tests to detect autonomic neuropathy and a history of related symptoms was taken there were 30 ( 60%) males and 20 ( 40%) females in the age range 30– 70 years . The five tests were carried out were, heart rate variation during deep breathing, HR response to valsalva, HR response to standing, BP response to sustained hand grip, BP fall in response to standing. Resting ECG (to measure QTc interval) fasting plasma glucose and 2hr., post prandial plasma glucose were done to each patient. RESULTS: Of these 50 patients 34(68%) had evidence of neuropathic abnormality of parasympathetic involvement 19(38%)patients 13(26%), patients had evidence of combined parasympathatic and sympathatic involvement and only 2(4%), patients had only sympathetic involvement. Increase incidence was seen in older age group and poor glycemic control. Autonomic neuropathy more common in patients who had the disease for more than 5 yrs. There was no correlation with prolonged QTC intervals. CONCLUSION: Diabetic ANP is a common complication and related to poor diabetic control and the duration of diabetes. While it is not associated with prolonged QTC interval . | ||
| Keywords | ||
| KEYWORDS; type II diabetes sympathetic and parasympathetic nervous system | ||
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