Evaluation of the Role of Gabapentin and/or Omega-30in Uremic Pruritus for Patients Undergoing Hemodialysis | ||
| Al-Mustansiriyah Journal for Pharmaceutical Sciences | ||
| Article 1, Volume 17, Issue 2, December 2017, Pages 132-140 | ||
| Authors | ||
| Saad Abdulrahman Hussain; ; Ali JassimAl; Kadhim Ali Kadhim; Sinan Forat Hussein | ||
| Abstract | ||
| Uremic pruritus, is chronic itching that occurs in patients with advanced or end-stage renal disease. It is one of the common symptoms in patients with the end-stage renal disease with approximately 60–90% of patients on hemodialysis(HD) suffering from this problem. This study was designed to evaluate the efficacy and safety of prescribing Gabapentin and Omega-3 in combination or aloneofor0relieving uremicopruritus0in Iraqi patients undergoing hemodialysis. The results showed that all the three involved regimens (gabapentin, omega-3, and the combination of both drugs) had significantly reduced the pruritus score. Furthermore, the combination was significantly superior to other regimens in reducing pruritus score, while no significant effect was observed by all the regimen soon interleukin-6 or on parathyroid hormone serum levels.In Conclusion, Gabapentin 100mg plus 1000mg omega-3 based fish oil capsules containing 120mg DHA and 180mg EPA is superior to each drug alone in reducing pruritus score in a sample of Iraqi patients. | ||
| Keywords | ||
| Gabapentin; Omega; Uremic Pruritus; hemodialysis | ||
|
Statistics Article View: 61 PDF Download: 30 |
||