Synthesis and characterization of new complexes of schiff bases derived from "sulfanilamide" with metal ions Hg+2, Zn+2 and evaluation their biological activity | ||
| karbala journal of pharmaceutical sciences | ||
| Article 1, Volume 7, Issue 11, September 2016, Pages 299-313 PDF (0 K) | ||
| Authors | ||
| ; Safaa A. Al-Samarrai; Malath Kh. Rasheed | ||
| Abstract | ||
| A new four Schiff bases synthesized by the condensation of the aromatic amine compound: 4-amino benzenesulfonamide with the four aromatic aldehyde compounds: 4-chloroBenzaldehyde, 4-BromoBenzaldehyde, 4-HydroxyBenzaldehyde and 4-(N,N-dimethyl) aminoBenzaldehyde, Also a complexes of pervious ligands were synthesized with the metal ions with molarity ratio (1:2) M:L. The synthesized compounds were characterized by physical and spectroscopic measurements (IR spectrum and proton NMR spectrum, elemental analysis C.H.N, Molar conductivity). All the synthesized complexes were formed tetra-coordinate complexes and the supposed chemical formula of the consequent complexes:[M(L)2Cl2]. The Biological activity were evaluated for the synthesized compounds against two types of bacteria E.Coli and S.aureus, most of complexes shown anti-bacterial activity. | ||
| Keywords | ||
| Schiff bases; Complexes of Zinc and Mercury; sulfanilamide drug; Biological activity | ||
|
Statistics Article View: 95 PDF Download: 287 |
||