Synthesis and characterization of some new N-mannich bases for clonazepam | ||
karbala journal of pharmaceutical sciences | ||
Article 1, Volume 7, Issue 11, September 2016, Pages 246-255 PDF (0 K) | ||
Authors | ||
Maha S. H. Alnuaimi; Khalaf F Alsamarrai; Athraa Aameed jassim | ||
Abstract | ||
The N- Mannich bases (1-10) have been synthesized by reaction of clonazepam with formaldehyde or benzaldehyde and different secondary amines. The N-Mannich bases were subjected to physicochemical studies like melting point determination, TLC and yield%. The structures of mannich bases were characterized by IR, 1HNMR and 13CNMR spectroscopy. | ||
Keywords | ||
mannich bases; Clonazepam | ||
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