A Study Effect of Some Organic Solvent Aromatic Materials on Male Rats Fertility. | ||
| journal of al-qadisiyah for pure science(quarterly) | ||
| Article 1, Volume 12, Issue 3, September 2012, Pages 30-42 PDF (0 K) | ||
| Author | ||
| Wisam A.W.AL-Khalidi | ||
| Abstract | ||
| This study was applied to investigate the toxicity effect of two organic solvent aromatic materials toluene (0.5 , 1.0 , 1.5 ml/ kg) and xylene (0.5 , 1.5 ml/ kg) through intarperitone injection for 30 day. The results showed the following: A significant decrease (P < 0.05) in body weight and body weight gain at the end of the experiment to all groups treated with toluene and xylene compared to control groups. A significant decrease (P < 0.05) in genital weight organs including (testes , epidymis , prostate and seminal vesicle) in the groups treated with higher concentration (toluene , xylene) compared to control. A significant decrease (P < 0.05) in sperm parameters (sperms concentration , movement , the percentage of sperms viability and normality) compared to control . The statistical analysis showed a significant decrease (P < 0.05) in levels of gonadotropin hormones (FSH , LH) and level testosterone hormone in the groups injected with toluene , xylene compared to the levels of those hormones in control. It is concluded that there is a negative role and toxicity of organic solvent aromatic (toluene and xylene) on male rats fertility. | ||
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