Effect of terpenoid extract of Petroselinum crispum seed in some fertility parameters and blood parameters in white male rats. | ||
| journal of al-qadisiyah for pure science(quarterly) | ||
| Article 1, Volume 12, Issue 2, June 2012, Pages 44-53 PDF (0 K) | ||
| Authors | ||
| Afyaa Sabah Nassir Al-Hamdany; Haider Salih Jaffat Al-Shafeay | ||
| Abstract | ||
| This study was aimed to determine some of possible effects of Petroselinum crispum seed terpenoids Extract on albino male rats during effects levels hormone FSH , LH and Testosterone according to effect on spermatogenesis , body weight , the accessory glands (prostate, seminal vesicles) and some blood physiological parameters (Hb,RBC,WBC,PCV). the experiments were designed to evaluate used (40) adult male rats were randomly divided into four groups (control and three treatment ) animals of treatment group received the Petroselinum crispum seed trapenoids extract 100 , 200 and 300 mg / mg B. wt., respectively orally give 0.5 ml between day to day for 50 days while control group receive normal saline all periods treatment were recorded the body weight after and before treatment . animals were sacrified after 24 hr. last dose and heart blood sample for biochemical and physiological study and obtain testes and epididymis their according weight purpose histological study also weight prostate , seminal vesicles and compare with control group this results show: 1-A significant increase(P<0.05) in both body weight and accessory glands when compare with control group and compare between group treatment significant . 2-The result show significant increase (P<0.05) on all parameter in number of spermatogonic cells and leydig cells compare with control Group and compare between treatment group , the dose 300 mg / dl high significant and high level of testosterone ,FSH and LH . 3-A significant increase(P<0.05) in histological study parameters in spermatogenesis compare with control group . 4-A significant increase (P<0.05) in the average of Hb,RBC,PCV and compare between group treatment is significant while decrease non significant (P>0.05) in the average of WBC when compare with control group . This study recommends that intake of the terpenoids extract of parsely seeds for male patients who suffer from sexual impotency . | ||
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