Relation Between Plasma Levels of Vitamins C and E Antioxidents with Sociodemographic Factors During Pregnancy | ||
| IRAQI JOURNALOF COMMUNITY MEDICINE | ||
| Article 1, Volume 29, Issue 1, March 2016, Pages 32-37 | ||
| Authors | ||
| Hala H Jassim; Iman F Hassan; Shaimaa S Athab; Maha M Al-Bayati | ||
| Abstract | ||
| Background: Normal pregnancy induces profound changes in maternal physiology which promotes oxidative stress. Vitamins C and E are antioxidants that work as a defense against this oxidation process. Objective: To assess the plasma levels of the vitamins C and E at different trimesters of pregnancy and to correlate them with the sociodemographic factors of pregnant women. Method: A case control study had been conducted in Al-Kadhymia Teaching Hospital which enrolled 120 women. Ninety pregnant cases of 20 -40 years, 30 cases for each of the first, second and third trimesters were the study group and the control group were thirty cases of non-pregnant women of the same age group. Plasma level of vitamin C and E were estimated using high performance liquid chromatography (HPLC)method. Results: The plasma level of vitamin C was significantly different across the different trimesters of pregnancy and it was significantly lower than the control group P<0.001. Also the plasma level of vitamin C was significantly decreasing with increased parity and age P<0.05, and its level was higher in working pregnant women compared to the pregnant housewives. The plasma level of vitamin E was significantly decreasing through the three trimesters of pregnancy P<0.05. Conclusion: The plasma level of both vitamins C and E are reduced during pregnancy and life style and occupation have great impact on vitamin C level in plasma. There is significant declining in plasma vitamin C level with parity and increase in maternal age. | ||
| Keywords | ||
| Vitamins C and E; Antioxidants; Sociodemographic factors; Pregnancy | ||
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