Antibiotics Prophylaxis In Non-Perforated AppendicitisA Prospective Study | ||
| Al-Kindy College Medical Journal | ||
| Article 1, Volume 3, Issue 1, December 2006, Pages 49-51 | ||
| Author | ||
| Khaleel A Al-Mefreji | ||
| Abstract | ||
| Background: The haphazard use of antibiotics in some centers is increasing and causing more harmful complications than its benefit.Objective: To study the role of antibiotics prophylaxis in low-risk non-perforated acute appendicitis.Methods: This study was done at Al-Kindy Teaching hospital in the period between Jan. 1999-Feb. 2000. 100 cases of acute appendicitis selected prospectively to be involved in a study including the use of prophylactic antibiotic therapy versus none. Criteria for selection were; age range between 13-30 years, no additional preoperative risk factors (diabetic, pregnant ladies, patients on steroid or anti-cancer therapy were all excluded), proper aseptic operative technique performed. Patients were divided into two groups, group A (n =53) were given antibiotic prophylaxis per-operatively (1gm of cefizox I.V), while group B (n = 47) were given no antibiotics. Intraperitoneal cultures were taken prior to antibiotic therapy. All excised appendices were sent for histopathological examination. Follow up was up to 4 weeks.Results: The study showed no statistically demonstrable difference among patients in group A (antibiotic group) and group B (control) regarding duration of hospital stay, incidence of wound infection, incidence of delayed postoperative complications.Conclusions: Antibiotic prophylaxis can be safely omitted in low-risk patients with non-perforated acute appendicitis, careful aseptic technique is mandatory. Cultures of peritoneal cavity are not necessary, saving efforts and financial resources. Key words: Acute appendicitis, non-perforated appendicitis, antibiotic prophylaxis | ||
| Keywords | ||
| acute appendicitis; non; perforated appendidicts; antibiotic prophylaxis | ||
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