Study of Adenosine Deaminase(ADA)Enzyme Activity of Children Patients With Kala-azar in Ameria City/AL-Anbar Governorate | ||
| Journal of University of Anbar for Pure Science | ||
| Article 10, Volume 8, Issue 3, December 2014, Pages 58-62 | ||
| Document Type: Research Paper | ||
| DOI: 10.37652/juaps.2014.124110 | ||
| Authors | ||
| Ban M.Abbas; Wajeeh Y.AL-Ani; Muthanna M.Awad | ||
| College of Science, University of Anbar | ||
| Abstract | ||
| A study of the Activity Adenosine Deaminase of the infected children with kala-azar in ameria City/AL-Anbar Governorate, this study is conducted on a sample of 90 male and female children (the range of them between 3 months to 8 years) in the General Ameria hospital and healthy center in AL-Ameria (the period between November 2011 to the end of May 2012) distributed in two groups: the first group includes those who are kala-azar patients (60 subjects ) while the second one includes the control group (30 subjects) , then both groups are subdivided according to four types concerning their age: the first one is less than one year; the second ranges from 1 to 2 years; the third ranges from 3 to 4 years; the fourth includes those who are more than five years. The findings of the study show a significant increase in the activity of (ADA) in the serum of the infected children compared to control group at the probability level (p < 0.05) concerning effect of sex variable on the activity of (ADA), the study shows no significant difference between male and female infected children at the probability level (p < 0.05). As regarded age variable on the activity of (ADA), the study shows significant difference between the different types of infected children at probability level (p < 0.05). It also shows positive correlation relationship between (ADA) Enzyme and weight of the infected children at the probability level (p < 0.05 ) . | ||
| References | ||
|
1. Sukkar, F."Epidemology and control of Visceral Leishmaniasis in Iraq".Bull.End.Dis.,26:13-27. (1985).
2. Gillespie, S.H. and Pearson, R.D ."Principles and practice of clinical parasitology". John wily & Sons Ltd, England.PP:287.(2001).
3.Chapel,H.;Haeney,M.;Misbah ,S.and Snowden,N."Essentials of Clinical Immunology". 5thed. Blackwell. PP:50. (2006).
4. Kayser,F.H.; Bienz, K.A.; Eckert, J. and Zinkernagel, R.M."Medical microbiology". 11th ed. Thieme Stuttgart. New York.PP:493.(2005).
5.Kliegman ,R.M; Behrmand,R.E; Jenson,H.B; Stanton,B.F."Nelson Text Book of pediatrics". 18thed. saunders, Elsevier.PP:1468.(2007).
6. Franco, R. and Centelles, J.J." Adenosine deaminase inhibitors as therapeutic agents". Drugs of today. 25: 155-170. (1989).
7.الجلبی، قصی عبد القادر. میکائیل، محمد حسین. "فعالیة الادینوسین دی امینیز فی مصل الاشخاص المصابین بالحمى التیفوئیدیة او حمى مالطا او الملاریا". 7 مجلة علوم الرافدین، المجلد 11، العدد 4، ص 14–21. (2000). 8. Dixon, M. and Weeb, E.C. In "Tools of Biochemistry", Edited by coperol, T.G., Jhon Wiley, and sons. Pub. Academic press, Inc. New York. (1961).
9.الداغستانی، أنعام أحمد حمزة حسین. "دراسة لفعالیة وخواص انزیم الادینوسین دی امینیز فی خمیرة Candida albicans ومقارنته ببعض الخلایا حقیقیة النواة ". رسالة ماجستیر، کلیة العلوم، جامعة الموصل (2005). 10. Gaitanati , C. and Beis,I.:Cestod international Journal of parasitology. Vol. 15(6): 651-654. (1985).
11. Agawal,R.P., Sagar, S.M.,Parks, R.E.: Pharmacology. Vol.24: 693-701.(1975).
12. Smillie, R.M." The breakdown of the adenosine phosphatase by brain tissue" . Arch, Brochem . Biophy. Vol. 67: 213-244. (1957).
13. Yasuda,J.,Tanabe,T.,Hashimoto,A.andToo,k:Br.Vet.J.Vol.152 (4): 485-488.(1996).
14. Smyth, J.F. and Harrap, K.R.: Biochem Pharmacol . Vol. 27: 2371-2374. (1977).
15.علی، اسماء عبد العزیز. "فعالیة انزیم ادینوسین دی امینیز فی المصل،وغدة التوثة ونخاع العظم للفئران البیض المصابة بالرؤیسات الأولیة للمشوکات الحبیبیة المعرضة لتیار کهربائی مستمر". مجلة جامعة الموصل، کلیة التربیة – قسم علوم الحیاة .(2009). 16. Carson,A.and Seemiller,E. " Effect of adenosine deaminas inhibition upon human lymphocyte blastogenesis". J.Clin. Invest. Vol.57: 247-282. (1976).
17. Paris,M.A.,Gakis, C.,Brudauri, M.and Pndereoni, G."Adenosine deaminase activity in pleural effusions . an aid to differential diagnosis" . Br.Med.J. Vol.2: 1751-1752. (1978).
18. Franco, R., Valenzuela, A., Lluis, C. and Blanco, J. "Enzymatic and extraenzymatic role of ecto-adenosine deaminase in lymphocytes". J. Immuno. Rev. Vol: 161: 27-42. (1998).
19. مروة شکیب ذنون أحمد الراوی،." المتغیرات الفسلجیة والمناعیة فی دم النساء المصابات بداء المقوسات فی مدینة الرمادی". رسالة ماجستیر، کلیة العلوم، جامعة الأنبار (2010). 20. Erel,O.; Kocyigit,A.; Gurel,M.S.; Bulut,V.; Seyrelc ,A.and ozdemir ,y. "Adenosine deaminase activities in sera, lymphocytes and Granulocytes in patients with cutaneous leishmaniasis".Mem Inst Oswaldo cruz,Rio de janeiro, vol.93(4):491-494 .(1998).
21. Kadhim,S.H.; Mahdi,S.A.; Gazally,M.E." Study of some purine Metabolic Enzymens in Sera of Patients with Renal Failure". Medican Journal of Babylon .vol.7No.1-2 (2010).
22. Al-Marsomi,H.Th." Adenosine Deaminase (ADA) in Rheumationl Ar thritis in Patients(RA)". J.Fac.Med.Baghdad.,Vol.51,No.2,(2009).
23.الحمدانی، هبة الله عادل یوسف. "دراسة دور البکتیریا الهوائیة واللاهوائیة فی إحداث المضاعفات بعد العملیات الجراحیة". رسالة ماجستیر، کلیة التربیة للعلوم الصرفة، جامعة الأنبار (2009). 24. Giusti, G."Adenosine deaminase .In Methods of Enzyme Analysis".2ed.Edited by: H.U. Bergmeyer. Academic Press.pp:1022-1099. (1981).
25. Karaman,U.; Beytur,L.; Kiran,T.R. and Cemil,C."Adenosin Deaminase level in the Serum of patients Toxoplasma gondii Seropositive and Giardia intestinalis".African J. of Microbiology Research. Vol..3(10):654-657.(2009).
26. Gakis,G.;Calia,M.;Naitana, A.G.;Orto, A.N. and AContu: Chest. Vol.99:1555-1556. (1991). | ||
|
Statistics Article View: 2,181 PDF Download: 50 |
||