Synthesis of Some New 2-thioxoimidazolidin-4-one Derivatives (part I ) | ||
| Ibn Al-Haitham Journal For Pure And Applied Science | ||
| Article 1, Volume 29, Issue 3, December 2016, Pages 88-102 | ||
| Author | ||
| Amjad Gali Aliwi | ||
| Abstract | ||
| This research includes the synthesis of new series of heterocyclic compounds. Reaction of 2-nitro benzylidene)thiosemicarbazide(1) with ethyl chloro acetate gave (2-nitro benzylidene amino)-2-thioxomidazolidine-4-one(2) ,treatment(2) with methyl iodide to give(3)which was reacted with hydrazine to give 2-hydrazinyl-1-[(2-nitrobenzylidene)amino]- 1H-imidazol-5(4H)-one, andreation of compound(2) with aromatic aldehydes to give 5-arylidene -3-({2-nitro benzylidene}amino)2-thioxo-3,5-dihydro-4H-imidazole-4-one(5a,5b), which was reacted with ethyl aceto acetate to give 4-aryl-1-[2-nitrobenzylidene, amino -6-oxo-2-thioxo octa hydro-1H-benzo[d]imidazole-5-carboxylate and followed synthesis of β-lactamederivtives(9a,9b) by treatment derivatives(8a,8b)schiff bases with chloro acetyl chloride .some new compounds were characterized by of some protone NMR of them and IR spectroscopy | ||
| Keywords | ||
| thiosemicarbazone; chalcone; beta lactone; imidazolidin; One | ||
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