Synthesis and Characterization of Some Heterocyclic Compound Tetrazole from Schiff Base | ||
| journal of al-qadisiyah for pure science(quarterly) | ||
| Article 1, Volume 16, Issue 3, July 2016, Pages 94-103 PDF (0 K) | ||
| Author | ||
| Hala Shakier Lihames | ||
| Abstract | ||
| Abstract A series of five membered ring, the tetrazole have been synthesized via Schiff base with sodium azide in the presence dry acetone at(50-55)Co to give the following compounds:- 1- 10-Methyl-3,6-bis(5-phenyl-1H-tetrazol-1-yl)-4a,10-dihydroacridine 2- 3,6-bis(5-(3,5-dimethylphenyl)-1H-tetrazol-1-yl)-10-methyl-4a,10-dihydroacridine. 3- 3,6-Bis(5-(2-Bromophenyl)-1H-tetrazol-1-yl)-10-methyl-4a,10- dihydroacridine. 4- 3,6-bis(5-(3-methoxy,5-hydroxyphenyl)-1H-tetrazol-1-yl)-10-methyl-4a,10-dihydroacridine. The derivatives have long been known to possess hypnotics activity and it is may be to get hypnotics activity from the newly prepared compounds. | ||
| Keywords | ||
| Tetrazole; Sodium azide; Schiff Base | ||
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