Staphylococcus aureus Nasal Carriage and Obesity among Patients with Type Two Diabetes Mellitus | ||
| Iraqi Journal of Science | ||
| Article 1, Volume 57, Issue 4, September 2016, Pages 2840-2848 | ||
| Authors | ||
| Sarah L. Hamad; Alice K. Agop Melconian | ||
| Abstract | ||
| The study aimed to find an association between Type two diabetes mellitus (T2DM) patients, obesity and the rate of nasal carriage of Staphylococcus aureus (NCSA) producer of TSST-1 in patients with T2DM compared with non-diabetic control groups. T2DM patients and control subjects were selected from outpatient of "The Specialist Center for Diseases of Endocrine and Diabetes" in Baghdad. The subjects were divided into 4 groups: Group I included 21 obese T2DM patients; Group II included 20 lean T2DM patients; Group III included 20 obese as control group and Group IV included 21 lean as control group. The study included sample with size (n= 82), male and female, with the ages ranged from 35 to 75 years, and the patients were not on any kind of anti-diabetic treatment. A total number of the nasal carriage S. aureus isolates were 38, of them 23 S. aureus (56.1 %) were isolated from the groups of patients with T2DM and 15 S.aureus isolates (38.46 %) were isolated from the control groups. Molecular method was used to detect the presence of tstH gene in S. aureus isolates indicating that the presnce of toxic shock syndrome toxin-1. The results revealed the presence of this gene in 12 (63.16%) S. aureus isolates collected from T2DM patients and 7 (36.84 %) isolates collected from control groups. | ||
| Keywords | ||
| Staphylococcus aureus Nasal Carriage; Obesity; Type Two Diabetes Mellitus; Toxic Shock Syndrome Toxin | ||
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