Synthesis and Characterization of New Oxazepine and Oxazepane Derived From Schiff Bases | ||
| journal of kerbala university | ||
| Article 1, Volume 12, Issue 2, June 2016, Pages 96-125 PDF (0 K) | ||
| Author | ||
| Sawsan Khdeaur Abbas | ||
| Abstract | ||
| In this work new bis -1,3-oxazepine and bis 1,3- oxazepane - 4,7- dione derivatives have been synthesized by cycloaddition reaction type [2+5→7] of maleic, phthalic and succinic anhydrides to synthesized Schiff bases derivatives . ortho-Tolidine was condensed with different aromatic aldehydes (4-hydroxy3-methoxy benzaldehyde, 4- isopropyl benzaldehyde, 2- formyl furan, 2,5-dimethoxybenzaldehyde and 4-chlorobenzaldehyde) in presence of glacial acetic acid as catalyst in absolute ethanol to give schiff bases derivatives A1-A5 respectively. The resulting Schiff bases derivatives A1-A5 were then introduced in [2+5→7] cycloaddition reaction with each maleic ,phthalic and succinic anhydrides in dry benzene to give new bis-1,3-oxazepine,1,3- oxazepane-4,7-dione derivatives A6-A11 and A12-A16 respectively.The synthesized target compounds A6-A11 and A12-A16 have been characterized by (C.H.N.)elementary micro analysis and the spectroscopic methods including FT-IR , 1H NMR | ||
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