Causes of fluctuation of estradiol level during ICSI cycle | ||
journal of kerbala university | ||
Article 1, Volume 12, Issue 2, June 2016, Pages 15-21 PDF (0 K) | ||
Author | ||
Aseel J. Al-bderi | ||
Abstract | ||
Eighty eight subfertile women involved in the study . All of them were subjected to controlled ovarian hyperstimulation during intracytoplasmic sperm injection cycle(ICSI) . Measurement of serum estradiol (E2) level was done at day 2 of their menstrual cycles .Second reading was done at day of HCG injection (where ovum size reach 16-22 mm).Third reading of serum E2 was done at the day of pickup of the ovum (before the pickup ) and at the time of pickup follicular fluid(FF) E2 was also measured. The results show that E2 in blood in day 2 is significantly higher in those with BMI≥25. The result show significant difference in E2 in blood which is higher in polycystic ovarian syndrome (PCO) in day2 of cycle and higher in non PCO group in day of HCG. There was significant positive correlation between the level of E2 in blood in day of pickup and in the FF .There reveal highly significant difference in the E2 level in blood in different days. The result show highly significant difference in the E2 level in different days in PCO group. The result show highly significant difference in the E2 level in different days in non PCO group. Correlation between serum E2 in day of pickup and E2 in follicular fluid among PCO group show significant positive correlation between E2 in day of pickup and E2 in FF. Correlation between serum E2 in day of pickup and E2 in FF among non PCO group show significant positive correlation between E2 in day of pickup and E2 in FF. | ||
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