Histological Changes of Cervix in Ovariectomized Indigenous Rabbits | ||
| Al-Mustansiriyah Journal for Pharmaceutical Sciences | ||
| Article 1, Volume 16, Issue 2, December 2016, Pages 45-52 | ||
| Authors | ||
| Muna R.A; Dhyaa Ab. Abood; Jehan M. Rajab | ||
| Abstract | ||
| Histological changes which occurred in the cervix of the ovariectomized rabbits without hormone and with hormones injection were investigated. A total of 45 female rabbits were divided into three groups, the first group was used as a control, while, the second and third groups were used for experiments. In control group the tunica mucosa thrown into branched folds which lined with simple cuboidal to columnar epithelium, and a lamina propria was well vascular dense irregular collagenous connective tissue and a tunica muscularis displayed double layers of smooth muscle fibers. In ovariectomized group without hormones injection, the tunica mucosa showed delicate mucosal folds which lined with low simple cuboidal epithelium and the tunica muscularis was very thin layer, and a significant decreased in the height and thickness of mucosal folds, thickness of lamina propria and tunica muscularis. In ovariectomized groups with hormones injection, the cervix was very thick walled organ and their mucosal folds were the tallest, pyramidal shaped and their epithelium turned into simple columnar epithelium. The thickness of tunica muscularis was increased due to their two layers those intermingled with much of collagen bundles. Statistically, a significant (P<0.05) increased in the values of all parameters. The present study concluded that that cervix in doe has a narrower lumen with huge collagenous connective tissue content that increased in response to steroid hormones, in addition to hyperplasia and hypertrophy, consequently for keeping intrauterine during the preimplantation stage and pregnancy | ||
| Keywords | ||
| cervix; ovariectomy; Hormones | ||
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