Towfiq amine, S., Ibrahim, A., Ahmed Mohammed, A. (2016). Indirect Determination of Amitriptyline Hydrochloride by Square Wave Voltammetry of SnCl2.2H2O. Alustath, 11(1), 89-100.
Suham Towfiq amine; Ali Ibrahim; Asmaa Ahmed Mohammed. "Indirect Determination of Amitriptyline Hydrochloride by Square Wave Voltammetry of SnCl2.2H2O". Alustath, 11, 1, 2016, 89-100.
Towfiq amine, S., Ibrahim, A., Ahmed Mohammed, A. (2016). 'Indirect Determination of Amitriptyline Hydrochloride by Square Wave Voltammetry of SnCl2.2H2O', Alustath, 11(1), pp. 89-100.
Towfiq amine, S., Ibrahim, A., Ahmed Mohammed, A. Indirect Determination of Amitriptyline Hydrochloride by Square Wave Voltammetry of SnCl2.2H2O. Alustath, 2016; 11(1): 89-100.

Indirect Determination of Amitriptyline Hydrochloride by Square Wave Voltammetry of SnCl2.2H2O

Tikret Journal of Pharmaceutical Sciences
Article 1, Volume 11, Issue 1, December 2016, Pages 89-100
Authors
Suham Towfiq amine; Ali Ibrahim; Asmaa Ahmed Mohammed
Abstract
A simple, fast and sensitive electroanalytical method consist studying the square wave of SnCl2.2H2O at hanging mercury dropping electrode in aqueous solution for the indirect determination of (AMI) drug. SnCl2.2H2O has revealed a major reduction potential at (-0.450) Volt against the reference electrode (Ag/AgCl/Sat.KCl). The calibration curve in the Phosphate buffer as the supporting electrolyte at pH=2 was constracted. The range concentrations up to (0.99X10-5–9.91X10-5) M, the correlation coefficient (r= 0.9989) and then studied the decreased of peak current of the drug by the (HMDE) behavior in the presence of SnCl2.2H2O. Results were as follow: The calibration curves were (0.316 X10-6 -3.136 X10-6) M and thismethods was successfully applied to determination of AMI in apharmaceutical formulations.
Keywords
Amitriptyline hydrochloride; Square wave voltammetry
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