Synthesis and spectroscopic studies of some Azetidin-2-one derivatives from Benzidine and S-Benzylthioglycolic acid via Schiff base | ||
Diyala Journal For Pure Science | ||
Article 1, Volume 10, Issue 3, August 2014, Pages 14-31 | ||
Authors | ||
Mustafa Y.Jamal; Saadon A. Aowda | ||
Abstract | ||
A series of four membered ring of azetidin-2-one (11-20) have been synthesized via Schiff bases(1-10) by reaction of different aromatic aldehyde with un substantiated benzidine in absolute ethanol and two or three droop glacial acetic acid then reflux for (2-3) hours . Schiff bases then reacted with S-Benzylthioglycolic in the presence of triethylamine with phosphorusoxychloride using dry methylene dichloride under inert nitrogen atmosphere at 0 ˚C. to give us the corresponding azetidin-2-one. The structural of these compounds were monitored and confirmed by using TLC , spectroscopic tools as IR ,1H NMR, and Elemental analysis. | ||
Keywords | ||
Imines; Schiff bases; Benzidine; lactam; Four member ring; Staudinger reaction; Ketene | ||
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