The Frequency of Epstein-Barr Virus Infection As A Pathogenic Agent In Laryngeal Carcinoma of Iraqi Patients Demonstrated By LMP-1 Expression | ||
| Journal of University of Babylon | ||
| Article 1, Volume 24, Issue 3, April 2016, Pages 787-794 | ||
| Author | ||
| Mazin J. Mousa | ||
| Abstract | ||
| The frequency of Epstein-Barr Virus (EBV) antigen; latent membrane protein-1 (LMP-1) expression in cases of laryngeal carcinomas was investigated by immunohistochemical staining technique. Fifty-six cases were included in this work; all cases of laryngeal carcinomas were squamous cell carcinomas with different degrees of differentiation. Immunohistochemical staining results revealed 60.7% positive staining results in overall cases, distributed according to the degree of differentiation almost equally (60% in well differentiated, 64.5% in moderately differentiated and 60% in poorly differentiated). The concordance of cigarette smoking with LMP-1 expression was high (96%). These results indicate the highly possible oncogenic effect of EBV infection on the development of laryngeal carcinomas in Iraqi patients. | ||
| Keywords | ||
| Laryngeal carcinoma; EBV; LMP | ||
|
Statistics Article View: 167 PDF Download: 100 |
||