HYPERTENSION AND OBESITY IN RELATION TO HIGH SENSITIVITYC-REACTIVE PROTEIN AND LIPID PROFILE IN IRAQI PATIENTS | ||
| Journal of Al-Nahrain University - Science | ||
| Article 1, Volume 12, Issue 4, December 2009, Pages 145-150 | ||
| Authors | ||
| Baydaa Ahmed Abed; Esam Noori Salman Al-Kirwi | ||
| Abstract | ||
| AbstractIntroduction:High sensitive C-reactive protein (hs-CRP) is one of new inflammatory markers which has beenproposed as independent risk factor for cardiovascular disease, and it is positively associated withbody weight. Little is known, however, about the utility of (hs-CRP) and other biomarkers in obesehypertensive Iraqi patients.Objectives:To examine the hypothesis that there is a relation between obesity, hypertension and a chroniclow-grade inflammatory status (represented by high hs-CRP).Patients and Method:A total number of 99 patients stratified according to hypertension and obesity into two groups:1. Obese hypertensive: Body mass index (BMI > 30 kg/m2 and blood pressure (BP) >140/90 mmHg± history of taking anti hypertensive medications), n = 65, Age = (56.02 ± 4.379) years,BMI = (35.68 ± 4.78) kg/m².2. Over weight normotensive: (BMI > 25 kg/m² and < 30 kg/m2, BP < 140/90 mmHg), n = 34,Age = (56.44 ± 3.17) years, BMI = (26.06 ± 3.05) kg/m².Assessment of (hs-CRP) and lipid profile (total serum cholesterol (s.chol), serum triglyceride(s.TG), low density lipoprotein (LDL), and high density lipoprotein (HDL) was done.Results:The (Mean ± SD) of (hs-CRP) in the patients and controls were (5.74 ±2.15) mg/l and(2.14 ± 0.85) mg/1 respectively, (P < 0.001). The (Mean ± SD) of cholesterol for cases and controlwere (215.17 ± 33.3) mg/dl and (197.81 ± 27.3) mg/dl respectively, (P < 0.05). For HDL were (51.31 ±7.45) mg/dl and (54.63 ± 5.091) mg/dl respectively, (P < 0.05). For LDL were (136.9 ± 32.87) mg/dl and(117.81 ± 24.73) mg/dl respectively, (P < 0.005). For BMI were (35.68 ± 4.78) kg/m2 and(26.06 ± 3.05) kg/m2 respectively, (P < 0.001).Conclusions:There is an elevation of serum level of (hs-CRP) in hypertensive obese subject in comparison with lowlevels in control group | ||
| Keywords | ||
| Hypertension; CRP; Obesity; Overweight; Lipid profile | ||
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