* Evaluation of interleukins (IL-1α and IL-18)in the sera of patients and associated cases of male infertility in AL-Najaf AL-Ashraf Governorate. | ||
| Magazine of Al-Kufa University for Biology | ||
| Article 1, Volume 0, Issue 0, September 2017, Pages 12-18 | ||
| Authors | ||
| Kais KhudhairAbdulabbasALhadrawi; SihamJasim Mohsen AL- Kaabi; Ihsan Edan .AL-Saimary | ||
| Abstract | ||
| A total of 328 seminal fluid samples were collected from infertile patients with various types of infertility; Azoospermia, oligozoospermia, asthenozoospermia, teratozoospermia aged between 19 to 60 years, in comparison with control group (Normospermia) for the period from 25/3/2013 to 17/8/2013. The following results had been obtained:- The interleukins (IL-1α and IL-18) concentration were measured in the present study by using enzyme linked Immune sorbent assay (ELISA). The result illustrated that there are highly significant correlation between IL-1α concentration in infertile patients and bacterial infection . There are elevation in IL-1α concentration reached to 35.9 mg/dl in comparison with uninfected infertile patients and control group (2.95 and 2.88) mg/dl respectively . It has been found elevation of IL-18 concentration in infertile patients with bacterial infection reached to 394.15mg/dl and 214.97 and 186.74 mg/dl for uninfected infertile patients and control group respectively with highly significant differences between concentration of IL-18 (P˂0.001) . All of these findings evidenced that there are strong relationships between immunological markers (Immunoglobulin ;IgG , IgM ,IgA and cytokines ;IL-1α and IL-18) that measured in various groups with bacterial infections may be enhanced immunological responses –especially –in infected infertile patients in comparison with other group. | ||
| Keywords | ||
| Allantvih Azoospermia; and the lack of sperm Oligospermia; and a weakening of sperm Asthenozoospermia; and deformation of sperm Teratozoospermia; azoospermia; Oligozoospermia; Asthenozoospermia; Teratozoospermia | ||
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