Synthesis and Characterization of Some New Benzimidazole Derivatives | ||
| Baghdad Science Journal | ||
| Article 1, Volume 13, Issue 1, February 2016, Pages 82-88 | ||
| Authors | ||
| Sahar T.Adday; Abdel-Amir M. Fenjan | ||
| Abstract | ||
| In this paper the new starting material 2-(5-chloro-1H-benzo[d]imidazole-2-yl) aniline (1) was synthesized by the condensation reaction of 4-chloro-o-phenylenediamine and anthranilic acid .The new Mannich base derivatives were synthesized using formaldehyde and different secondary amines to synthesize a new set of benzimidazole derivatives(2-5). Also, the new Schiff-base derivatives (6-10) were synthesized from the reaction of compound (1) with various aromatic aldehydes and the closure-ring was done successfully using mercapto acetic acid to get the new thiazolidine derivatives(11-12).These new compounds were characterized using some physical techniques like:FT-IR Spectra and 1HNMR Spectra. | ||
| Keywords | ||
| Benzimidazole; Mannich bases; Schiff; thiazolidine | ||
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