The Efficacy of Some Lactic Acid Bacteria in Some Biological Indicators and Obesity in Rats | ||
Journal of Tikrit University For Agriculture Sciences | ||
Article 1, Volume 16, Issue 1, March 2016, Pages 164-176 | ||
Authors | ||
Falah S. Dawood; Karkaz M. Thalij | ||
Abstract | ||
The study was conducted in order to determine their effects some species of lactic acid bacteria on body weight, biological blood parameters, further the balance of gut natural flora, to see its role in obesity after giving orally at bacterial groups forms with skimmed milk to 42 days for female growing rats. The effect of orally feed from microbial groups were caused significantly increased (p<0.05) in laboratory animals body weights at six week compared with the initial weights. while the body weights of bacterial orally feeding rats groups were decreased significantly at the two to six week compared with the control rats group . The results also showed that oral administration of lactic acid bacteria species were cause significant decrease in each of the triglycerides, serum cholesterol, low density lipoproteins, glucose and total protein concentration and increased of high density lipoproteins value while did not change the albumin and globulin compared with values in the control group animals. The results were show as reduced the activity of Alkaline phosphatase (ALP) and Aspartate amino transferase (AST) while didn’t effects on Alanine amino transferase (ALT) compared with the control group values. The value of the cortisol hormone, which is an indication to the incidence of obesity has significantly decreased if animals groups given from probiotics compared with the control animals group which at 16.5 µg/disllter. The oral administration of probiotics may cause significant decrease of Enterobacteriaceal species in all areas of gut and opposite increased lactic acid bacteria species counts, compared with animals control group. The conclusion from the study results that’s of lactic acid bacteria species given orally had caused a decrease in body weight and thus lack of obesity cases, as well as improve the health status of laboratory animals. | ||
Keywords | ||
Probiotics; Body weights; Cortisol; Obesity; Rats | ||
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