Effect of sodium benzoate in the level of thyroid stimulating hormone and the level of thyroxin hormone in mature albino male rats | ||
| journal of kerbala university | ||
| Article 1, Volume 10, Issue 4, December 2014, Pages 295-299 PDF (0 K) | ||
| Abstract | ||
| The study was conducted in the animal house of Education college,University of Al-Qadisiyah during the month of October in order to study the effect of sodium benzoate on the levels of certain biochemical parameters in adult albino male rats with three months old, The results of the orally treatment of mature albino male rats with three different concentrations of sodium benzoate (50, 100, 200) mg/kg for three different durations( one, two and three)week were showed a significant decrease (P<0.05) in the levels of the thyroid stimulating hormone and thyroxine in both 100 mg/kg (G2) and 200 mg/kg (G3) groups during two weeks duration of treatment also in the 50 mg/kg (G1),G2,and G3 groups during three weeks duration of treatment in comparison with control groups. The comparison between durations of each treatment was shown that the levels of both thyroid stimulating hormone and thyroxine were significantly decreased (P<0.05) during three weeks duration in comparison with one weak duration of treatment in G3 group . | ||
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